First Round
US Union Douala (Cameroon)-0/1-Zamalek  
Date: 13 Mar 2016
Scorer: Mohamed Koffi 58"
Line-Up: Ahmed El-Shennawi / Omar Gaber / Ahmed Dewidar / Mohamed Koffi / Hamada Tolba / Tarek Hamed / Maarouf Youssef (Ahmed Tawfik) / Mahmoud Abdel Razek "Shikabala" / Ayman Hefny / Moustafa Fathi (Hazem Emam) / Emmanuel Mayuka (Basem Morsi)

Zamalek-2/0-US Union Douala (Cameroon)  
Date: 19 Mar 2016
Scorers: Mahmoud Abdel Monem "Kahraba" 27" / Ahmed Tawfik 89"
Line-Up: Ahmed El-Shennawi / Omar Gaber / Ahmed Dewidar / Mohamed Koffi / Hamada Tolba / Maaeouf Youssef / Tarek Hamed / Mahmoud Abdel Razek "Shikabala" (Moustafa Fathi) / Ayman Hefny / Mahmoud Abdel Monem "Kahraba" (Basem Morsi) / Emmanuel Mayuka (Ahmed Tawfik)

Second Round
Zamalek-2/0-Mouloudia Olympique de Béjaïa (Algeria)  
Date: 9 Apr 2016
Scorers: Mahmoud Abdel Monem "Kahraba" 59" / Ahmed Hammoudi 82"
Line-Up: Ahmed El-Shennawi / Hazem Emam / Ahmed Dewidar / Mohamed Koffi / Hamada Tolba / Omar Gaber / Tarek Hamed / Maarouf Youssef / Ayman Hefny (Emanuel Mayuka) / Mohamed Ibrahim (Basem Morsi) / Mahmoud Abdel Monem "Kahraba" (Ahmed Hammoudi)

Mouloudia Olympique de Béjaïa (Algeria)-1/1-Zamalek  
Date: 19 Apr 2016
M.O.B Scorer: Fawzi Yaya 56"
Zamalek Scorer: Ahmed Hammoudi 88"
Line-Up: Ahmed El-Shennawi (Mahmoud Abdel Rehim "Gennesh" 45+1") / Ahmed Tawfik / Ahmed Dewidar (Ali Gabr 80") / Mohamed Koffi / Hamada Tolba / Hazem Emam / Tarek Hamed / Maarouf Youssef / Ayman Hefny / Mohamed Ibrahim (Ahmed Hammoudi 59") / Mahmoud Abdel Monem "Kahraba"

Quarter Final - Group B
Enyimba (Nigeria) 0/1 Zamalek
Date: 19/6/2016
Zamalek Scorer: Basem Morsi 8"
Zamalek Line Up: Ahmed El-Shennawi / Hazem Emam / Ahmed Dewidar / Ali Gabr / Hamada Tolba / Mohamed Ibrahim (Ahmed Hassan Mekki 90") / Ahmed Tawfik / Tarek Hamed / Maarouf Youssef / Mahmoud Abdel Monem "Kahraba" (Ibrahim Abdel Khalek 74") / Basem Morsi

Zamalek 1/2 Mamelodi Sundowns (South Africa)
Date: 17/7/2016
Zamalek Scorer: Mohamed Ibrahim 37"
Zamalek Line Up: Ahmed El-Shennawi / Hazem Emam / Mohamed Koffi / Ali Gabr / Mohamed Adel Gomaa / Mahmoud Abdel Razek "Shikabala" (Maarouf Youssef) / Ahmed Tawfik / Tarek Hamed / Ayman Hefny / Mohamed Ibrahim (Moustafa Fathi) / Basem Morsi (Emmanuel Mayuka)

Mamelodi Sundowns (South Africa) 1/0 Zamalek  
Date: 27/7/2016
Zamalek Line Up: Ahmed El-Shennawi / Hamada Tolba (Moustafa Fathi) / Ahmed Dewidar / Ali Gabr / Ali Fathi / Mahmoud Abdel Razek "Shikabala" (Mohamed Salem) / Ahmed Tawfik / Ibrahim Abdel Khalek / Maarouf Youssef / Ramzy Khaled (Ayman Hefny) / Basem Morsi

Zamalek 1/0 Enyimba (Nigeria)
Date: 15/8/2016
Zamalek Scorer: Basem Morsi 63" Pen
Zamalek Line Up: Ahmed El-Shennawi / Ahmed Tawfik / Islam Gamal / Ali Gabr / Ramzy Khaled / Ayman Hefny (Emmanuel Mayuka) / Ibrahim Salah / Tarek Hamed / Maarouf Youssef / Moustafa Fathi (Mahmoud Abdel Razek "Shikabala") / Basem Morsi (Stanley Ohawuchi)

Semi Final
Zamalek 4/0 WAC Casablanca "Wydad" (Morocco) 
Date: 16/9/2016
Zamalek Scorers: Mahmoud Abdel Razek "Shikabala" 4" / Ayman Hefny 18" / Basem Morsi 49" / Moustafa Fathi 73" Pen
Zamalek Line Up: Ahmed El-Shennawi / Ahmed Tawfik / Ali Gabr / Islam Gamal / Ramzy Khaled (Ahmed Dewidar 74") / Mahmoud Abdel Razek "Shikabala" (Stanley Ohawuchi 78") / Tarek Hamed / Ibrahim Salah / Maarouf Youssef / Ayman Hefny (Moustafa Fathi 65") / Basem Morsi 

WAC Casablanca "Wydad" (Morocco) 5/2 Zamalek
Date: 24/9/2016
Zamalek Scorers: Basem Morsi 35" / Stanley Ohawuchi 81"
Zamalek Line Up: Ahmed El-Shennawi / Ahmed Tawfik / Ali Gabr / Ahmed Dewidar / Islam Gamal / Moustafa Fathi (Mahmoud Abdel Razek "Shikabala" 46") / Tarek Hamed / Ibrahim Salah / Maarouf Youssef / Stanley Ohawuchi (Ramzy Khaled 90+1") / Basem Morsi (Ayman Hefny 68")

Final
Mamelodi Sundowns (South Africa) 3/0 Zamalek 
Date: 15/10/2016
Zamalek Line Up: Ahmed El-Shennawi [-3] (Mahmoud Abdel Rehim "Gennesh" [0] 63") / Ahmed Tawfik / Ali Gabr / Islam Gamal / Maarouf Youssef / Ayman Hefny / Tarek Hamed / Ibrahim Salah / Mahmoud Abdel Razek "Shikabala" (Ramzy Khaled 54") / Stanley Ohawuchi / Basem Morsi (Moustafa Fathi 75") 

Zamalek 1/0 Mamelodi Sundowns (South Africa) 
Date: 23/10/2016
Scorer: Stanley Ohawuchi 65"
Zamalek Line Up: Mahmoud Abdel Rehim "Gennesh" / Ramzy Khaled (Mahmoud Abdel Razek "Shikabala" 76") / Ahmed Dewidar / Ali Gabr / Maarouf Youssef / Ahmed Tawfik / Ayman Hefny (Emmanuel Mayuka 85") / Tarek Hamed (Ibrahim Salah 86") / Moustafa Fathi / Stanley Ohawuchi / Basem Morsi