The Nobel Prize
in Chemistry 1905The Nobel Prize
in Chemistry 1905In regard to von Baeyer's work, Professor A. Lindstedt, President of the Royal Swedish Academy of Sciences, made the following statement, on December 10, 1905
A characteristic feature of chemical science is the close
interaction between theory and practice, between pure science and technology,
which is here assuming ever greater importance. This feature became especially
prominent during the last decades of the nineteenth century. Many a time has
a reaction, carried out with small quantities of substances in the research
worker's test tube, by being correctly evaluated and systematically applied,
achieved a revolution in the chemical industry, and in such fashion that emphasis
has shifted from one industrial centre to another, or that completely new branches
of industry have been created.
One such new branch which was hardly dreamed of fifty years ago, but which now
provides work for many thousands and spreads its products all over the world,
is the preparation of organic dyestuffs from coal tar.
Among the living research workers who have contributed directly or indirectly
to the unique development of the tar-dyestuff industry the place of honour goes
to the Professor at Munich University, Adolf von Baeyer, for his researches
into the composition of indigo as well as into the triphenyl methane
dyestuffs.
Indigo, the gorgeous pigment of the indigo plant, has been considered the most
important of all organic pigments on account of its beauty and colour fastness,
and the annual tribute which the West used to pay India for it amounted to a
very considerable sum. To reproduce the pigment by synthetic methods and make
it more easily obtainable was therefore an exceptionally inviting task for chemical
research.
The complex and unique composition of indigo, however, made this also one of
the hardest of tasks. Here there could be no question of one of those casual
discoveries, which by happy accident seem to achieve half the work. Years of
work were required for even von Baeyer's acumen and experimental skill to achieve
the necessary insight into the pigment's chemical composition and to be able
to manufacture it from simpler constituents. Even after the purely scientific
part of the work had been completed it still took a number of years to make
the results obtained from research applicable to technology.
Von Baeyer succeeded in producing indigo synthetically in three principal ways,
namely from ortho-nitrophenylacetic acid, from ortho-nitrocinnamic
acid and from ortho-nitrobenzaldehyde and acetone. This paved the way
for the reproduction of indigo from raw material obtainable without much difficulty
from coal tar. And if the problem of producing indigo industrially has now been
solved from the technical as well as the economic point of view, this is entirely
due to von Baeyer's basic work in the fields in question.
The result is striking. Already the price of indigo has fallen to a third of
its former price, and Germany's export of synthetic indigo in 1904 could be
valued at over 25 million marks. This shows that the synthetic product has been
able to compete with decisive success against the natural product. The effects
of this discovery, which was made in the Munich University laboratory, can already
be traced as far as the banks of the Ganges, and the time is probably not far
distant when the immense fields, which up to now have been used for cultivation
of the indigo plant will instead become available to produce cereals and other
foodstuffs for India's starving millions.
Simultaneously with his analyses within the indigo group, analyses moreover
which exerted a far-reaching influence upon the development of organic chemistry
and directed research into new channels, von Baeyer was active with no less
success in another sphere of the chemistry of organic dyestuffs. The stimulus
was given by his discovery of a new group of beautifully coloured compounds,
the so-called phthaleins, of which only the eosin pigments, highly important
to industry, and the rhodamin dyes derived from them, may have particular mention
here. In a series of masterly experiments von Baeyer demonstrated several years
ago the chemical nature of the phthaleins and showed that, just like the already
known rosaniline dyes, they may be classified as derivatives of the hydrocarbon
triphenylmethane. In recent years - more exactly, from 1900 on - von Baeyer
has resumed his work on triphenylmethane, and from this a new conception of
the chemical composition of pigments and in general of the connection between
the optical properties of organic substances and their interior atomic structure
has been to a high degree prepared.
The dyestuffs studied by von Baeyer belong to the main category of organic substances
usually classified under the name of aromatic compounds, which differ decisively
from the other organic substances - the so-called aliphatic or fatty acid series
- both in their properties and in their behaviour in reaction. In fact this
difference has been considered so great that it has caused the division of the
whole of organic chemistry into two separate halves: the chemistry of aliphatic,
and of aromatic substances. Nevertheless, one of the main tasks of scientific
research is to try to bridge the gulfs dividing different sciences, or different
branches of the same science. In this respect, too, von Baeyer has carried out
notable work in his research, remarkable alike from the experimental as well
as from the theoretical point of view, on the so-called hydroaromatic compounds.
With these compounds, he has found the transitional form between the two main
series just mentioned and by application of the new conception and the new method
to the terpenes and the species of camphor occurring in nature and also important
for technology, he has opened up fields for synthetic work which were previously
inaccessible.
The research-worker's way to a discovery varies according to the nature of his
goal. He may, after quite a short period of trial-and-error, see unsuspected
vistas open up before him, but he may as well have to cut a slow and certain
path to his goal by stubborn persistence.
Von Baeyer's work in the fields here mentioned has been of this latter variety.
His relevant work is spread out over a long period of time and has continued
up to the present day, but only in recent years has it been possible to appreciate
and survey in its full extent its exceptional importance. The Royal Swedish
Academy of Sciences therefore feels it is acting in full accord with the Nobel
Charter in awarding this year's Nobel Prize for Chemistry to the Professor at
the University of Munich, Geheimrat Adolf von Baeyer, for the services he
has rendered to the development of organic chemistry and the chemical industry
through his work concerning organic dyes and hydroaromatic compounds.
As sickness prevents the recipient from being present here today, the Prize
will be conveyed to him through His Excellency, the German Ambassador.
From Nobel Lectures, Chemistry 1901-1921, Elsevier Publishing Company, Amsterdam, 1966