This game is suppose to have over 250 Pokemon!
Each one will now even have it's own gender, so you can breed them and make baby pokemon.
The images in battle will be improved so Pokemon will look more realistic.
They will now be diurnal and nocturnal, so you may have to wait until the right time of day to use them.
You can trade Pokemon from the Red/Blue versions to the Gold/Silver version, but you can't do it the other way around because the Red/Blue version would understand the new Pokemon.
Plus the Pokemon will evolve even farther than they did in the Red/Blue version!
Pokemon Not Found in Gold:
Ekans/Arbok (you can get them at the Game Corner)
Vulpix/Ninetales
Meowth/Persian
Pokemon Not Found in Silver:
Sandshrew/Sandslash (you can get them at the Game Corner)
Growlithe/Arcanine
Mankey/Primape
Pokemon Not Found in Either:
Bulbasaur/Ivysaur/Venusaur
Charmander/Charmeleon/Charizard
Squirtle/Wartortle/Blastoise
Omanyte/Omastar
Kabuto/Kabutops
Articuno
Zapdos
Moltres
Mewtwo
Mew