Derek Harold Richard Barton was
born on 8 September 1918, son of William Thomas and Maude Henrietta Barton.
In 1938 he entered Imperial College, University of London, where he obtained
his B.Sc.Hons. (1st Class) in 1940 and Ph.D. (Organic Chemistry) in 1942. From
1942 to 1944 he was a research chemist on a government project, from1944-1945
he was with Messrs. Albright and Wilson, Birmingham. In 1945 he became assistant
lecturer in the Department of Chemistry of Imperial College, from 1946-1949
he was I.C.I. Research Fellow. In 1949 he obtained his D.Sc. from the same University.
During 1949-1950 he was Visiting Lecturer in the Chemistry of Natural Products,
at the Department of Chemistry, Harvard University (U.S.A.). In 1950 he was
appointed Reader in Organic Chemistry and in 1953 Professor at Birkbeck College.
In 1955 he became Regius Professor of Chemistry at the University of Glasgow,
in 1957 he was appointed Professor of Organic Chemistry at Imperial College,
which position he still holds.
In 1950, in a brief paper in Experientia entitled "The Conformation of
the Steroid Nucleus", Professor Barton showed that organic molecules in general
and steroid molecules in particular could be assigned a preferred conformation
based upon results accumulated by chemical physicists, in particular by Odd
Hassel. Having chosen a preferred conformation, it was demonstrated that the
chemical and physical properties of a molecule could be interpreted in terms
of that preferred conformation. In molecules containing fixed rings, such as
the steroids, there resulted a simple relationship between configuration and
conformation, such that configurations could be predicted once the possible
conformations for the products of a reaction could be analysed. Thus the subject
"conformational analysis" had begun. Barton later determined the geometry of
many other natural product molecules using this method. Conformational analysis
is useful in the elucidation of configuration, in the planning of organic synthesis,
and in the analysis of reaction mechanisms. It will be fundamental to a complete
understanding of enzymatic processes.
Prof. Barton was invited to deliver the following special lectures: 1956, Max
Tischler Lecturer at Harvard University; 1958, First Simonsen Memorial
Lecturer of the Chemical Society; 1961, Falk-Plaut Lecturer, Columbia University;
1962, Aub Lecturer at Harvard Medical School; Renaud Lecturer at Michigan State
University; Inaugural 3 M's Lecturer, University of Western Ontario; 1963, Hugo
Müller Lecturer of the Chemical Society; 3 M's Lecturer at the University
of Minnesota; 1967, Pedler Lecturer of the Chemical Society; 1969, Sandin Lecturer
at the University of Alberta; 1970, Graham Young Lectureship, Glasgow.
In 1958 Prof. Barton was Arthur D. Little Visiting Professor at Massachusetts
Institute of Technology, Cambridge, Mass.; in 1959 Karl Folkers Visiting Professor
at the Universities of Illinois and Wisconsin.
In 1954 Derek Barton was elected to Fellowship of the Royal Society, in 1956
he became Fellow of the Royal Society of Edinburgh; in 1965 he was appointed
member of the Council for Scientific Policy of the U. K.; in 1969 he became
President of Section B, British Association for the Advancement of Science,
and President of the Organic Chemistry Division of the International Union of
Pure and Applied Chemistry.
Professor Barton holds the following honours and awards: 1951, First Corday-Morgan
Medal of the Chemical Society; 1956, Fritzsche Medal of the American Chemical
Society; 1959, First Roger Adams Medal of the American Chemical Society; 1960,
Foreign Honorary Member of the American Academy of Arts and Sciences; 1961,
Davy Medal of the Royal Society; 1962, D. Sc.h.c. Montpellier; 1964, D. Sc.h.c.
Dublin; 1967, Honorary Fellow of the Deutsche Akademie der Naturforscher "Leopoldina";
1969, Honorary Member of Sociedad Quimica de Mexico; 1970, D.Sc.h.c.
St. Andrews: Fellow of Birkbeck College; Honorary Member of the Belgian Chemical
Society; Foreign Associate of the National Academy of Sciences; Honorary Member
of the Chilean Chemical Society; D.Sc.h.c., Columbia University, New
York; 1971, First award in Natural Product Chemistry, Chemical Society (London);
D.Sc.h.c., Coimbra (Portugal); Elected Foreign Member of the Academia
das Ciencias de Lisboa; 1972, D. Sc.h.c. University of Oxford; Longstaff
Medal of the Chemical Society.
Derek Barton was first married to Jeanne Kate Wilkins but this marriage was
later dissolved. He is now married to Christiane Cognet, a Professor of the
Lycée français de Londres. He has one son, W.G.L. Barton, by his
first marriage.
From Nobel Lectures, Chemistry 1963-1970, Elsevier Publishing Company, Amsterdam, 1972
This autobiography/biography was written at the time of the award and later published in the book series Les Prix Nobel/Nobel Lectures. The information is sometimes updated with an addendum submitted by the Laureate. To cite this document, always state the source as shown above.
For more updated biographical information, see:
Barton, Derek H.R., Some Recollections of Gap Jumping. Oxford University
Press, Oxford, 1998.
Sir Derek Barton died on March 16, 1998.