SR 22 begins at Jct I-82/US 12 Exit 50 near Buena, heads south to Jct US 97 at Toppenish, then turns and heads ESE via Mabton to Jct I-82/US 12 Exit 82 at Prosser. SR 22 is 35.84 miles long.
Before 1964, SR 22 from Buena to Toppenish had been part of US 97 and from Toppenish to Prosser, part of SSH 3A.
Interstate Routes
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