1st round
BYE 

2nd round 
Ismaily-2/0-TCO "Terrible de la Côte Ouest Boeny" (Madagascar)-(Ahmed Khairy 77" / John Antwi Duku 79") 
Date: 17/3/2013
Ismaily's Line-up: Mohamed Sobhi / Mohab Said / Ayman El-Mohammadi / Abdel Hamid Sami / Karim Mos’ad (Sherif Ragab 70”) / Ahmed Khairy / Mohamed Soliman "Hommos" (Ndubuisi Godwin Eze 55”) / Amr El-Soulyia / Mohamed Hamed “Mido” (Omar Gamal 46”) / Essam Ali / John Antwi Duku

 

TCO "Terrible de la Côte Ouest Boeny" (Madagascar)-2/2-Ismaily

Ismaily Scorers: John Antwi Duku / Ibrahim Hassan 90+3") 

Date: 7/4/2013
Ismaily's Line-up: Mohamed Sobhi / Karim Mos’ad (Ayman El-Mohammadi) / Mahmoud Metwali / Abdel Hamid Sami / Ahmed Abdel Aziz "Moody" / Mahmoud Hamad / Mohamed Sherif (Ibrahim Hassan) / Amr El-Soulyia / Ahmed El-Gamal (Mohamed Soliman "Hommos") / Omar Gamal / John Antwi Duku

3rd round 
Ahly Shendi (Sudan)-0/0-Ismaily 

Date: 19/4/2013
Ismaily's Line-up: Mohamed Sobhi / Ayman El-Mohammadi / Abdel Hamid Sami / Mahmoud Metawli / Karim Mos’ad (Sherif Ragab 69”) / Ahmed Khairy / Mohamed Soliman "Hommos" (Ibrahim Hassan 46") / Mahmoud Hamad / Amr El-Soulyia / John Antwi Duku / Ndubuisi Godwin Eze (Omar Gamal 64”)

 

Ismaily-0/0-(4:3 P)-Ahly Shendi (Sudan) 
Penalty Shooters: Amr El-Solayya, John Antwi Duku, Ahmed Khairi & Sameh Abdel Fadhil All scored
Date: 3/5/2013
Ismaily's Line-up: Mohamed Sobhi / Ahmed Abdel Aziz “Moodi” / Abdel Hamid Sami / Sameh Abdel Fadhil / Mahmoud Hamad (Ahmed El-Gamal 74”) / Ahmed Khairy / Mohamed Soliman "Hommos" (Mahmoud Abdel Aziz 65”) / Amr El-Soulyia / Mohab Said (Ibrahim Hassan 59”) / John Antwi Duku / Ahmed Ali

Added Round of 16 vs Losers of Champions League 3rd round 
CA Bizerte "Benzert" (Tunisia)-3/0-Ismaily
Date: 19/5/2013
Ismaily's Line-up: Mohamed Sobhi / Mohamed Sherif / Abdel Hamid Sami / Sameh Abdel Fadhil / Mahmoud Metwali / Mahmoud Hamad / Ahmed Khairy / Essam Ali (Mohamed Soliman "Hommos" 65”) / Omar Gamal / John Antwi Duku / Ahmed Ali (Ndubuisi Godwin Eze 88")
 

Ismaily-1/0-CA Bizerte "Benzert" (Tunisia)

Ismaily Scorers: Ahmed Khairy 42"

Date: 2/6/2013
Ismaily's Line-up: Mohamed Sobhi / Ahmed Abdel Aziz “Moodi” (Mohamed Soliman "Hommos" 76”) / Abdel Hamid Sami / Sameh Abdel Fadhil / Sherif Ragab (Mohab Said 88") / Ahmed Khairy / Amr El-Soulyia / Mohamed Sherif / Omar Gamal / John Antwi Duku / Ahmed Ali (Ndubuisi Godwin Eze 86”)