Champions League 1985
Semifinal
Zamalek 1/0 Royal Army Forces "(FAR Rabat) (Al-Gaish Al-Malaky)" (Morocco)(Tarek Yehia)
Royal Army Forces (Morocco) 1/0 (4-3 Pen) Zamalek

Champions League 1986
Final
Zamalek 2/0 Africa Sports (Cote d'Ivoire) (Ayman Younis 2)
Africa Sports (Cote d'Ivoire) 2/0 (2-4 Pen) Zamalek

Champions League 1993
Final
Kotoko (Ghana) 0/0 Zamalek
Zamalek 0/0 (7-6 Pen) Kotoko (Ghana)

Champions League 1996
Semifinal
CS Sfaxien "Safaques" (Tunisia) 1/0 Zamalek
Zamalek 1/0 (4-3 Pen) CS Sfaxien "Safaques" (Tunisia) (Mohamed Sabry)
-
Final
Shooting Stars (Nigeria) 2/1 Zamalek (Tarek Moustafa)
Zamalek 2/1 (5-4 Pen) Shooting Stars (Nigeria)(Medhat Abdel Hady / Ayman Mansour)

Super Cup 1996
Zamalek 0/0 (4-2 Pen) Mekawleen

Cup Winners' Cup 2000
2nd round
Zamalek 2/1 Coffee "Ethiopian Bunna" (Ethiopia) (Medhat Abdel Hady / Abdel Halim Ali)
Coffee "Ethiopian Bunna" (Ethiopia) 2/1 (2-4 Pen) Zamalek(Abdel Halim Ali) Penalty Scorers: Medhat Abdel Hady / Amr Fahim  / Ayman Abdel Aziz / Mohamed Sabry

Champions League 2003
2nd round
Simba SC (Tanzania) 1/0 Zamalek
Zamalek 1/0 (2-3 Pen) Simba SC (Tanzania) (Abdel Halim Ali)

Champions League 2008
2nd round
Zamalek 2/0 Africa Sport (Core d'Ivoire)  (Amr Zaki 30' / Mohamed Aboul Ela 43')
Africa Sport (Core d'Ivoire) 2/0 (4-5 Pen) Zamalek

Confederation Cup 2018
1st round
Wolaitta Dicha SC (Ethiopia) 2/1 Zamalek (Emad Fathi 36")

Zamalek 2/1 (3-4 P) Wolaitta Dicha SC (Ethiopia) (Ahmed Madbouli 45+2" Pen, 48")

Confederation Cup 2019
Final  
Renaissance Sportive de Berkane "Nahdat Berkane" (Morocco) 1/0 Zamalek 

Zamalek 1/0 (5-3 P) Renaissance Sportive de Berkane "Nahdat Berkane" (Morocco) (Mahmoud Alaa 55" Pen)