(Powerpuff Girls #5) - Atop his Townsville Volcano-Top Observatory headquarters Mojo Jojo looked out over Townsville, livid that all the money in the Townsville Bank, Armory and diamond district wasn’t his thanks to the meddling of the Powerpuff Girls. He spotted the Girls playing baseball and Buttercup threw a pitch too hard, knocking out one of Bubbles’ teeth. Buttercup blamed Bubbles for not paying attention because she was busy petting a cat, while Blossom told Buttercup she played too rough and they’d see what Dr. Utonium had to say about the situation. Utonium assured Bubbles she wasn’t broken and that all children lost their baby teeth. He calmed her down by saying the Tooth Fairy would leave a quarter under her pillow. Mojo Jojo had a brainstorm, planning on stealing bubbles’ lost tooth to create a Super-Superior Drill that could cut through steel, and that night he visited Bubbles disguised as the Tooth Fairy. With his Super-Superior Drill he robbed the bank, the armory and the diamond district. The Mayor called in a panic after Mojo Jojo robbed him, letting the Powerpuff Girls know he was using Bubbles’ tooth for crime. The Powerpuff Girls energy beams had no effects on the drill, but Bubbles gummed it up using a caramel apple, and Mojo Jojo was sent away in a paddy wagon.

(Powerpuff Girls #6) - Mojo Jojo constantly hungered for the destruction of the Powerpuff Girls, but at the moment he hungered for food and rang up Tony’s Pizza. When he decided to change his order he called again, but misdialed and realized he’d discovered the Powerpuff Girls hotline. Posing as the Mayor he called the Powerpuff Girls, telling them an invisible monster was eating all the food at Malph’s Market. With the Girls occupied on the other side of Townsville Mojo Jojo robbed the Townsville Bank. He called them again as the Mayor, warning them about a fire-breathing water monster wrecking havoc at the Townsville Museum, using their absence to steal a giant laser cannon. The Powerpuff Girls were frustrated with being led on wild goose chases and confronted the Mayor, who assured them he hadn’t called them recently. Dr. Utonium told the Girls that Mojo Jojo now had a giant laser cannon, but wasn’t too worried because he’d need two giant batteries and an expensive focusing lens to power it. The mailman told Utonium he’d just delivered a focusing lens to Mojo Jojo. Mojo called the Girls about a three-headed tarantula attacking the waterfront, but Blossom saw through his trick. They confronted him at Battery World where he was trying to shoplift two giant batteries and beat him up and sent him to jail. The Powerpuff Girls got a call about a half-squid half-pickle monster attacking the Mayor’s office and assumed Mojo Jojo was making another prank call from jail. The monster was legit and the Mayor and Sara Bellum wondered why the Powerpuff Girls weren’t flying to the rescue.

(Powerpuff Girls #7) - The Powerpuff Girls had to go into action without Bubbles, who was obsessed with the children’s program Dr. Blowtop’s Land of Happy Show, and refused to leave her television set. Blossom and Buttercup stopped a rampaging monster, Mojo Jojo and Fuzzy Lumpkins while Bubbles was glued to the TV. Dr. Blowtop said everyone on his show had lost their happiness, and the only way they could get it back was for the kids watching the show to take money from their parents and send it to him. Blossom and Buttercup investigated when dozens of parents in Townsville found their money missing, and realized what was happening when Bubbles took Dr. Utonium’s money he hid in his mattress and the Townsville treasury from the Mayor and delivered it to Dr. Blowtop live on his show. Buttercup had been saying it was time for Bubbles to outgrow children’s shows and showed her that the Land of Happy was nothing but a television set. Dr. Blowtop lost his temper at having his plan foiled, blurting out that stealing money from the parents of Townsville was the first step in his scheme to become a famous supervillain. Bubbles realized she’d been tricked and had no problem wrecking Dr. Blowtop and his cast.

(Powerpuff Girls #11) - Fuzzy Lumpkins entered the Farmville County Fair’s Freakishly Large Produce Competition and was awarded the blue ribbon by the judges, who were worried he’d hurt them if he didn’t win. The Shutter Thug used his special camera to take a picture of Lumpkin’s prize-winning pumpkin, trapping it in the photo. Fuzzy demanded to know who stole his pumpkin and went on a rampage in Townsville. Dr. Utonium tried to take family photos with the Powerpuff Girls, but Buttercup kept making faces. The tension was broken when the Mayor and Sara Bellum phoned the hotline, asking the Girls to stop Fuzzy. The Powerpuff Girls beat down Fuzzy, but as he was being taken away by the police the shutter Thug took a picture of him, adding Fuzzy to his collection. Princess Morbucks attacked the Powerpuff Girls, accusing them of stealing her 100% mink teddy bear Mr. Blackwell, not realizing the Shutter Thug had added it to his collection. During the battle Shutter Thug took a picture of Morbucks and put her in his photo album. His next target was the Townsville Dam, and after a panicked call from the Mayor the Powerpuff Girls stopped a tidal wave caused by the released water by freezing it solid. Shutter Thug took the Girls picture and they found himself trapped in his photo album. Buttercup ripped the picture, allowing them to travel around the photo album, and the Powerpuff Girls picked up the Washington Monument, using it to tear through the album entirely and release all the shutter Thug’s captives. The Mayor and Sara thanked the girls for saving the city, but they were leery of having their picture taken by the press.

(Powerpuff Girls #12) - Pokey Oaks had a snow day and the Powerpuff Girls were excited to have a day off relaxing. Unfortunately the snow caused a number of emergencies and the Mayor called them about ice skaters who fell through the ice and an avalanche that buried cars. Dr. Utonium was trying to win the Cleanest Driveway in Townsville Award, so he kept having the girls shovel so he could win the prize from the reigning champion Ms. Keane. The Mayor and Sara Bellum debated over who to give the award to when the Abominable snowman ran rampant in Townsville. The girls beat he beast and then finally took some time for themselves to play in the snow. Dr. Utonium panicked while the girls were away and decided he had to keep the driveway clean himself. The Mayor arrived to give him his award and told the Powerpuff girls that Sara Bellum said to tell them good job on taking out the Abominable Snowman.

(Powerpuff Girls #13) - While Dr. Utonium and the Powerpuff Girls were grocery shopping at Malp’s Mojo Jojo hit the Girls with his new paranoia beam. The Powerpuff Girls all nearly avoided having a mental breakdown at Malph’s, and when they returned home they told Utonium they no longer trusted anyone, but he thought they were playing a game. Mojo Jojo gloated as the Powerpuff Girls turned against each other, and knew they’d no longer trust themselves before long. He trained the paranoia beam on their home, but Dr. Utonium discovered it when he was adjusting his antenna to collect cosmic radiation. The Powerpuff Girls realized Mojo Jojo was behind their woes because his paranoia beam had a tag saying “Property of Mojo Jojo.” The Girls confronted Jojo at his observatory headquarters, and he tried to claim his paranoia beam was a simple flashlight. They didn’t believe his story and turned the paranoia beam on Mojo Jojo, making him a wreck.

Dr. Utonium was a character from Cartoon Network’s The Powerpuff Girls cartoon that was licensed by DC Comics. This entry covers only his DC appearances.

Dr. Utonium's appearance in Powerpuff Girls #1 was reprinted in Powerpuff Girls #70 and Powerpuff Girls: Double Whammy #1.