Chaos had hit Raccoon City...Terror had spread across the city as fast as the T-Virus had. Infecting and diseasing numerous civilians, people tried to evacuate. But instead the rescue team had no choice but to baracade the city, so no one or something could get out spreading the diease. Almost everyone who hadn't died, were tortured by the T-Virus. There were only two survivors. Jill Valentine, who had experienced this threat once already, and actually lived to tell the tale, had been trapped again in the nightmare. Along with a local civilian, who had managed staying alive, by staying with Jill. They remained in a garage, staying out of the way of the zombies reach. Until they had no choice but to move out...

Jill tried to persuade the Local to come along with her, there was no other way. He refused, explaining that his daughter had already been taken and killed by the zombies. He ran in the back and locked himself in the back. Jill had no choice but to leave him...

As Jill explores the deserted remains of Raccoon City, she meets along with some of the members of Umbrella's Rescue team. Struggling to find saftey and escape this nightmare, they advance through Raccoon City looking for the rescue team to free them and get out of Raccoon city. This is the ultimate fight for their lives...