Dr. Curtis Connors lost his right arm while serving as an Army surgeon. Also a brilliant herpetologist, Connors became convinced he could apply his studies of certain reptiles' regenerative abilities to human physiology to help him to regain his limb. Isolating the reptile enzyme responsible for regeneration, he injected himself with an experimental formula of his own creation. The serum restored Connors' missing arm, but also triggered a horrific, body-wide mutation that transformed the hapless scientist into a savage, humanoid reptile calling itself the Lizard.
Shortly after Connors' apparent death in quicksand during the Lizard's battle with Spider-Man and Warrant, a huge bestial Lizard appeared. Spider-Man realized that not only had the Lizard survived, but this new monstrous transformation seemed to be permanent and the personality of Curt Connors appeared completely lost. However, when this savage mindless Lizard later unexpectedly encountered Dr. Connors himself, Curt became the true Lizard once again and saved his family by killing the "Lizard-clone". It was revealed that the Lizard-clone was a scientific accident resulting from an experimental formula being tested on a piece of the original Lizard's tail, which had then grown into a fully-formed second creature.
Current Version:
The Lizard I (The Gauntlet)
Other Versions:
The Lizard I
The Lizard II