| Pitcher's Name | W-L | ERA | G | SV | IP | H | ER | HR | BB | SO |
| Christy Mathewson | 16-15 | 2.41 | 40 | 2 | 280.2 | 221 | 75 | 17 | 38 | 183 |
| Red Ames | 17-12 | 1.83 | 39 | 0 | 266.2 | 189 | 54 | 17 | 49 | 142 |
| Dummy Taylor | 18-13 | 1.70 | 42 | 1 | 292.1 | 200 | 55 | 20 | 24 | 60 |
| Joe McGinnity | 13-14 | 2.50 | 35 | 0 | 256.0 | 234 | 71 | 14 | 30 | 89 |
| Hooks Wiltse | 20-10 | 1.29 | 49 | 1 | 299.1 | 158 | 43 | 16 | 33 | 109 |
| Claude Elliott | 3-1 | 0.58 | 41 | 6 | 77.1 | 23 | 5 | 5 | 2 | 4 |
