Combat Knife - Combat Knife, again...

H&K VP70 - Leon's handgun. The Heckler & Koch VP70 is the original polymer handgun. It was designed hand in hand with a buttstock that converted the pistol into a three round burst sub-machinegun when the stock was attached.

Browning HP - Claire's handgun. The Hi-Power is one of the most-used military service pistols of all time. It's an excellent choice due to it's cartridge, reliability, and high-capacity magazine.

Remington M1100-P - Leon's Shotgun...a more powerful weapon. Combine it with the custom shotgun parts to get a deadly custom shotgun! It can be obtained after Kendo dies and you walk to his body and press the action button or in the STARS office locker.

Bowgun - Claire's Bowgun...it shoots 3 arrows at a time...it can be obtained as Claire after Kendo dies. Walk over to his body pressing the action button to pick it up.

Desert Eagle .50 Action Express - Leon's magnum, You can get the custom parts to make a custom magnum. It uses DOT .50 A.E. rounds.

M79 Grenade Launcher - This is Claire's weapon, and it is very useful against tough enemies especially with the nice selection of 3 ammo types. |Grenade| Acid| Flame| rounds.

Flamethrower - Made by Umbrella Inc. This is useful against the plant creatures, the % gauge is set at 100. [Tip: Put it in the item box for more room. It takes up 2 item spaces in your inventory which it doesn't make up for in power.]

Spark Shot - Claire gets this weapon. It has a % ammo gauge like the flamethrower.

Colt S.A.A - The Colt Single Action Army is the bonus weapon Claire gets when you kill the Brad Vickers zombie ,and obtain the locker key for the picture developing room. "This is the greatest handgun ever made. Six shots...more than enough to kill anything that moves." - Revolver Ocelot

Gatling Gun - You get this weapon after beating the game with an A or B ranking. It takes a little while to get going ,but once it does, it tears the enemies apart.

Rocket Launcher - You get this if you beat the game with an A or B ranking as well. It can kill any enemy in one shot.