In Illinois, Federal Route 40 is an east-west route in the southern part of the state with a slight northeast-southwest tilt. Following very closely along Interstate 70, it enters the state at St. Louis, Missouri, and exits near Terre Haute, Indiana.
Information on US40 is broken down into 3 parts:
Missouri state line to Madison/Bond County line(includes Metro-East)
Madison/Bond County line to Effingham/Fayette County line (includes Vandalia)
Effingham/Fayette County line to Indiana state line (includes Effingham)