In Illinois, Federal Route 50 runs east-west, spanning the entire width of southern Illinois. It enters the state from Missouri along Interstate 255 on the southern outskirts of the St. Louis area, and it leaves by crossing the Wabash near Vincennes, Indiana.
Information on US50 is broken into 3 parts:
Missouri state line to St. Clair/Clinton County line
St. Clair/Clinton County line to Marion/Clay County line
Marion/Clay County line to Indiana border
