| Cleveland First Round Draft Picks | ||
| 1980 | Terry Kennedy | |
| 1981 | Jeff Reardon | |
| 1982 | Bobby Ojeda | |
| 1983 | Willie McGee | |
| 1984 | Greg Walker | |
| 1985 | Roger Clemens (#9 pick) | |
| 1986 | Brian Fisher | |
| 1987 | Dale Mohorcic | |
| 1988 | Sam Horn | |
| 1989 | Bryan Harvey | |
| 1990 | Sammy Sosa | |
| 1991 | Alex Fernandez | |
| 1992 | Chuck Knoblauch (#6 pick) | |
| 1993 | Roberto Hernandez | |
| 1994 | Aaron Sele (#8 pick) | |
| 1995 | Alex Rodriguez (#7 pick) | |
| 1996 | Ray Durham | |
| 1997 | Edgar Renteria (#1 pick) | |
| 1998 | Todd Helton (#10 pick) | |
| 1999 | Matt Mantei (#7 pick) | |
| 2000 | Scott Williamson (#10 pick) | |
| 2001 | Kelly Wunsch | |
| 2002 | Ichiro Suzuki (#1 pick) | |
| Joel Piniero (from GBr) | ||
| 2003 | Hank Blalock | |
| 2004 | Jason Phillips | |
| 2005 | J.D.Closser | |
| 2006 | Ervin Santana | |
| 2007 | Francisco Liriano | |
| 2008 | Josh Hamilton (from SL) | |
| Matt Garza | ||
| 2009 | Mike Aviles | |
| 2010 | Chris Coghlan | |
| 2011 | Starlin Castro (#10 pick- from SL) | |
| 2012 | none | |
| 2013 | Brandon Belt | |
| 2014 | Avisail Garcia | |
| 2015 | Masahiro Tanaka (#7 pick) | |
| 2016 | Kyle Schwarber (#7 pick from NE) | |
| 2017 | Tim Anderson (from SL) | |
| 2018 | Yoan Moncada (#2 pick from Gle) | |
| Reynaldo Lopez (from Yk) | ||
| 2019 | Gleyber Torres (#5 pick) | |
| 2020 | Eloy Jimenez (#3 pick from Mar) | |
| John Means | ||