| Southport First Round Draft Picks | |
| 1980 | David Palmer (#7 pick) |
| 1981 | Joe Charboneau (#6 pick) |
| 1982 | Hubie Brooks (#6 pick) |
| 1983 | Storm Davis (#10 pick) |
| 1984 | Cecilio Guante |
| 1985 | Ernie Camacho |
| 1986 | Ted Higuera |
| 1987 | Bob Tewksbury |
| 1988 | Bobby Thigpen |
| 1989 | Jose Bautista |
| 1990 | Roberto Kelly |
| 1991 | Delino Deshields (#7 pick) |
| 1992 | Mike Nagy (#5 pick) |
| 1993 | Dave Fleming (#5 pick) |
| 1994 | Jason Bere (#5 pick) |
| 1995 | Bob Hamelin (#4 pick) |
| 1996 | Marty Cordova |
| 1997 | Chan Ho Park (#10 pick) |
| 1998 | Fernando Tatis |
| 1999 | none |
| 2000 | Carlos Beltran (#1 pick) |
| 2001 | Terrence Long (#6 pick) |
| Santiago Perez (from VT) | |
| 2002 | Shea Hillenbrand (#10 pick) |
| 2003 | none |
| 2004 | Scott Podsednik |
| 2005 | Aaron Miles (#8 pick) |
| 2006 | Ryan Zimmerman |
| 2007 | Ronny Paulino |
| 2008 | Joba Chamberlain (from Cre) |
| 2009 | Jeff Clement (from Dun) |
| 2010 | none |
| 2011 | Buster Posey (#2 pick) |
| 2012 | Jason Kipnis |
| 2013 | Yu Darvish (#5 pick from Yk) |
| Norichika Aoki (from Alb) | |
| 2014 | Brad Miller |
| 2015 | Drew Hutchison |
| 2016 | Kevin Pillar |
| 2017 | Andrew Benentendi (#6 pick) |
| 2018 | Matt Olson (#10 pick) |
| 2019 | Willy Adames (#8 pick) |
| 2020 | Bryan Reynolds |
| 2021 | Jake Cronenworth |
| 2022 | James Kaprielian |
| 2023 | Julio Rodriguez (#2 pick) |