Limburger hires the Loogie Brothers or better known as the "scum of the universe" to destroy the Biker Mice. Of course they were unable to complete their mission so Limburger decides to use their horrific odor to stink up the city. The citizens of Chicago are forced to leave or suffer a attack on their nasal passages. The Biker Mice decide to approach them with their guns a blazing and their deodorizing cans ready for action.

Evil Eye Weavil and the Pukes of Hazzard decide to try to divide and conquer the mice by using their "hostility ray." Will the mice split up for good or will they forgive and forget? One things for sure... "It's Tail Whippin' Time."