
The best way to insult people is to say something that is to hard for them to comprehend.
aberration - n - a deviation from the normal (a weirdo) My brother is such an aberration.
abhorrent - adj. - disgusting My brother is so abhorrent.
appall - v - to fill with horror My brother appalls me.
belligerent - adj. - warlike My brother is so belligerent (this was used on the show "Dharma and Greg"!)
blasé - adj. - bored with the world Stop acting so blasé! (this was used on the movie "Titanic"!)
boorish - adj. - rude My brother is so boorish.
corpulent - adj. - fat Bill is so corpulent.
despot - n - a tyrant Hitler was a despot.
diabolic - adj. - devilish My brother is so diabolic
eccentric - adj. - unusual Katie's mom is so eccentric.
fastidious - adj. - fussy My brother is so fastidious.
flay - v - to skin I will flay my brother if he goes in my room.
gauche - adj. - tactless My brother is so gauche.
gaudy - adj. - cheap and showy My brother is so gaudy.
grotesque - adj. - bizarre My brother is so grotesque.
junket - n - an outing (this isn't an insult, I just love the word) We went on a junket.
infinitesimal - adj. - very small My brother's brain is infinitesimal.
irascible - adj. - easily angered Diana is very irascible.
loathsome - adj. - repulsive My brother is so loathsome.

miscreant - n - a villain My brother is a miscreant.
naïve - adj. - clueless My brother is so naïve.
nauseated - adj. - sickened My brother makes me nauseated.
nemesis - n - a rival Colorado is Detroit's nemesis (in hockey).
obtuse - adj. - stupid My brother is so obtuse.
onerous - adj. - troublesome My brother is quite onerous.
ostentatious - adj. - showy That coat is quite ostentatious.
paragon - n - a model of excellence My brother is definitely not a paragon, but I am.
repugnance - n - a dislike I have a repugnance for my brother.
sinister - adj. - evil My brother is so sinister.
slovenly - adj. - messy Your room is quite slovenly.
tacky - adj. - in poor taste My brother is so tacky.
tawdry - adj. - cheap and showy My brother is tawdry.