I'm assuming most of you are already aware of the following events but I've included it for the benefit of those who are not familiar with Spidey's origins.
Spider-Man was first introduced in the comic Amazing Fantasy #15 (August 1962). Peter Parker, a Senior at Midtown High School, receives his powers when bitten by a radioactive spider in a science demonstration. This bite endowed him with the proportional strength and agility of a spider along with a keen "spider sense". After discovering these powers Peter hires an agent and tries to make some money in television. He had became a professional wrestler. One night a he had the chance to catch a burglar fleeing from the T.V. studio, but he refused because he didn't think he should try and be a hero. A few days later the same burglar killed his Uncle Ben. That night, as Spider-Man, Peter apprehends the murderer of his beloved uncle but is plagued with guilt, thinking that if he would have stopped the burglar when he first saw him his Uncle Ben would still be alive.
Spiderman's Greatest Enemies
