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| BUTTON COMBO | ATTACK NAME | DAMAGE |
| A Button | Left Jab | 2-4% |
| A Button (second) | Right Cross | 1-3% |
| A Button (third) | Toe Kick | 3-6% |
| A (while dashing) | Slide | 4-9% |
| Left or Right + A | Dr. Kick | 3-9% |
| Up + A | Uppercut | 4-10% |
| Down + A | Reflex Test | 4-9% |
| Smash Left or Right + A | Defibrillator | 9-27% |
| Smash Up + A | Ear, Nose and Throat | 7-21% |
| Smash Down + A | Surgical Sweep | 8-24% |
| A Button (in air) | Dr. Kick | 5-14% |
| Forward + A (in air) | Dr. Punch | 8-17% |
| Backward + A (in air) | Drop Kick, M.D. | 3-8% |
| Up + A (in air) | Bicycle Kick | 5-10% |
| Down + A (in air) | Bone Drill | 1-19% |
| Z or (R + A) | Grab | 0% |
| A or Z (while holding) | Eye Exam | 1-3% |
| Forward (while holding) | Routine Physical | 4-9% |
| Backward (while holding) | Traction | 6-12% |
| Up (while holding) | Check Up | 4-8% |
| Down (while holding) | Hospital Bed | 3-6% |
| MEGAVITAMINS | SUPER SHEET | SUPER JUMP PUNCH | DR. TORNADO |
Pig!!!!!! |
Left or Right + |
Up + |
Down + |
| Dr. Mario's Megavitamins dish out slightly more damage than Mario's Fireballs. They also have a wilder trajectory. Press the B Button to send a capsule flying toward your foe. | Press the Contol Sick Left or Right and hit the B Button to slap foes with the Super Sheet. Compared to Mario's Cape, the sheet has a shorter horizontal range but higher vertical range. | Even though Mario is wearing doctor's gear, he is still Mario and he still can jump. Dr. Mario's Super Jump Punch is identical to Mario's big-air move. Use it for more height while you're flying. | The whirling dervish that is Dr. Mari's Dr. Tornado sends foes flying to the left or right, while Mario's Tornado move sends foes staight up. Press Down and B to start turning. |
