Oct. 1998-: | Ph. D student at the University of Neuchâtel (Switzerland) in the research group of Prof. R.Neier |
1994-1997: | Diplôme d’Ingénieur
Chimiste de Ecole Nationale Superieure de Chimie de Mulhouse
(ENSCMu, French
‘Grande Ecole’ in Chemistry), majoring in medicinal and bioorganic chemistry.
Diplôme d’Etudes Approfondies (DEA), (MSc.equivalent) of the University of Haute-Alsace (UHA, France) in Organic and Macromolecular Synthesis, with honors. The practical work of these two Diploma were done in the Research group of Dr. M. Lang (Medicinal chemistry, Oncology, Novartis pharma Basel, Switzerland) and under the academic supervision of Pr. C. LeDrian. Licence de Chimie Physique (BSc.equivalent) of the University of Haute-Alsace. |
1991-94: | Classes Préparatoires,
math sup.-math spé. at Lycée
A.Schweitzer of Mulhouse:
3 years intensive course for entrance into a French "Grande Ecole". |
1991: | Baccalauréat C (eq. "A" levels) with honors at lycée J.Mermoz (Saint-Louis, France (068)) majoring in Maths, Physics and Chemistry. |
English: | Good level. |
German: | Fluent, (9 months placement in Basel, Switzerland). I speak also the alsacien dialect. |
Referees: | Prof. R. NEIER
(University of Neuchâtel, Switzerland)
Prof. C. Le DRIAN (ENSCMu, France) Dr. M. LANG (Novartis pharma, Basel, Switzerland) Dr. G. CARAVATTI (Novartis pharma, Basel, Switzerland) |
Oct. 1998-: | Ph. D.,
Assistant of the
University
of Neuchâtel in the research
group of Pr. R. Neier. Studies and applications of novel tandem reactions
Diels-Alder /[3 :3] sigmatropic rearrangement. Application to the total
synthesis of natural products as juvabione and the ibogamine Skeleton.
Supervision of laboratory of inorganic chemistry for the 1st year students in chemistry and pharmacy. Exercise sessions for the 3rd year students in advanced organic chemistry. Responsible for research project of 4th year students (advanced laboratory). Responsible for a diploma (MSc. eq.) student. Training of a 3 rd year laborant. |
1997-1998: | Military service as
Scientifique du contingent at the l’Institut
de Chimie des Surface et Interface (ICSI)
of Mulhouse (France).
Studies of the reduction of thionyle chloride in a porous environment to optimize a SOCl2/Li battery. Study of the influence of Teflon on the proprieties of the carbon electrodes. Work done in collaboration with the DGA, Alcatel, SAFT et and the CNRS. |
Aug-sep. 1997: | NOVARTIS,
Pharmaceutical Research, Basel. 2 months in the research group of Dr. G.
Caravatti .
Synthesis of peptidic inhibitors of the SH2 domain of the Grb2 protein. Peptidic synthesis in solution. |
Feb.-jul. 1997:
|
NOVARTIS,
Pharmaceutical Research, Basel. 7 months DEA placement in the research
group of Dr. M.Lang, under the guidance of Dr. G. Caravatti.
Synthesis of non-peptidic inhibitors of the SH2 domain of the Grb2 protein. Organic synthesis, heterocyclic chemistry, Suzuki coupling reaction. Classical analytic techniques were used (RMN, MS, IR, UV, HPLC, MPLC, GC, CHN...). |
1996: | HOFFMANN La ROCHE, Total Quality Management (TQM), Village-Neuf (France). 1,5 months in the analytical laboratory responsible for the treatment of wastewater. Analysis of the water and mire by the following methods DBO, MES, DCO, TOC, Dosages and checking the good yield of the purification station. Studies of the biodegradability of new organic products freshly used in new productions. |
Use of Macintosh and PC computers
and software (Microsoft Office, Isis Draw, Isis base, ChemDraw, Reference
Manager ).
Responsible for the electronic data bases research ( STN Chemical Abstracts on-line, SciFinder Scholar, Cross-fire Beilstein, Current Contents, Chemweb, ETHICS/Nebis). Presentation and communication skills from addressing the department in seminar and by poster. Member of the Conseil de L’Institut de Chimie of Neuchâtel 2000-2001. |
1999,
poster |
R.Neier, J.Velker, J.-Ph.Roblin, N.Soldermann 1999, Novel Tandem Reactions and their Applications in Synthesis. 36th National Organic Chemistry Symposium, University of Wisconsin, Madison, USA, 13-17.6 1999, poster 191. |
1999,
poster |
R.Neier, J.Velker, J.-Ph.Roblin, N.Soldermann 1999, Tandem Reactions and their Applications in Synthesis. 37th IUPAC Congress, Berlin, Germany, 14-19.8.1999, poster ORG-1-031, p.474. |
1999,
poster |
N.Soldermann, J.Velker, O.Vallat, R.Neier, Studies and application of the novel Diels-Alder/Ireland-Claisen tandem reaction. NSSC Herbstversammlung 1999 Basel, Chimia, 53, 7-8, 1999, 364, poster 156. |
2000,
poster |
N.Soldermann, O.Vallat,
R.Neier, Mechanistical Studies of the Diels-Alder / Ireland-Claisen Tandem
reaction, RSC-SCI Joint Meeting on Heterocyclic Chemistry 2000,
Folgaria (Italy),
poster. |
2000, publication | N.Soldermann, J.Velker,
O.Vallat, H.Stoeckli-Evans, R.Neier*, Application of the Novel Tandem-Process
Diels-Alder Reaction/Ireland-Claisen Rearrangement to the Synthesis of
(rac.)-juvabione and (rac.)-epijuvabione, Helv.Chim.Acta., 2000,
2266-2276.
Pdf file. |
2000,
communication |
N.Soldermann, J.Velker, R.Neier, Application
of the novel tandem process Diels-Alder / Ireland Claisen rearrangement
to the synthesis of (rac.)-Juvabione and (rac.)-Epijuvabione.
NSSC Assemblée d'automne 2000 Lausanne, Chimia, 53, 7-8, 2000, 452, poster 244. |
2001,
publication |
Jörg Velker, Nicolas Soldermann, Antonia Neels, Helen Stoeckli-Evans and Reinhard Neier* ,A Highly Stereoselective Tandem Sequence Diels-Alder Reaction/ Claisen Rearrangement starting from substituted (E)-Butadienyl-O,O-Keten Acetals, J.Chem.Soc., Chem.Com, submitted |
Sports: | Tennis, cycling, ski and fitness. |
Cultural: | Alsacien theatre in Village-Neuf.
Movies, BD’s, thrillers, new media and travel. |
Miscellaneous: | Brevet National de Secourisme
(BNS), and Reanimation with honors ( French national First aid diploma).
Brevet de Technique Générale du Sapeur Pompier, level 1. (French firemen diploma) Member of the SCS ( Swiss Chemical Society) and SFC (French Chemical Society). Driving license. |