N.A.I.A. Women's National Champions
Women's Outdoor 400-Meter Relay
| Year | School | Athletes | Performance |
| 2010 | Indiana Tech | Abigail Torian, Adela King, Chloe Brooks, Katelyn Lewis | 45.27 |
| 2010 | Oklahoma Baptist | Marissa Moseley, Shonda Drew, Verone Chambers, Gayon Evans | 45.47 |
| 2009 | Wayland Baptist (TX) | Latanya Nation, Kimberly Smith, Bianca Grant, Keliesha Ross | 45.27 |
| 2008 | Wayland Baptist (TX) | Latanya Nation, Kimberly Smith, Caroline Oladipo, Keliesha Ross | 46.22 |
| 2007 | Wayland Baptist (TX) | Patricia Mayers, Akisha Simmons, Caroline Oladipo, Keliesha Ross | 46.21 |
| 2006 | Missouri Baptist | Nikkita Holder, Rachel Baldwin, Laniece Clarke, Nickesha Anderson | 45.87 |
| 2005 | Langston (OK) | Damesha Sellers, Tasia Galbreath, Tatiana Simon, Dominique McDonald | 45.89 |
| 2004 | Lindenwood (MO) | Daveeta Shepherd, Carol Clarke, Danielle Norville, Genna Williams | 45.33 |
| 2003 | Lindenwood (MO) | Meila Fleming, Carol Clarke, Danielle Norville, Angilla Corlette | 46.34 |
| 2002 | Central State (OH) | Marsha Hayles, Vida Nsiah, Avery Sterling, Adetooke Aladefa | 46.40 |
| 2001 | Florida Memorial | Dorcia Cash, Sallie Green, Lorraine Jackson, Sharlene McQueen | 46.20 |
| 2000 | Life (GA) | Mishrah Crooks, Timishi Gonzalez, Monica Twum, Meosha Hubbard | 45.48 |
| 1999 | Life (GA) | Sherese Collie, Lucyann Richards, Mishrah Crooks, Camille Clarke | 45.66 |
| 1998 | Southern-New Orleans | Stacian Brown, Keisha Miller, Altrice Taylor, Naomi Mills | 45.90 |
| 1997 | Southern-New Orleans | Lesakay Morgoridge, Altrice Taylor, Tameca Williams, Cydonie Mothersill | 45.41 |
| 1996 | Central State (OH) | Chanteau White, Beverly Grant, Ronalee DAvis, Catherine Pomales | 44.95 |
| 1995 | Southern-New Orleans | Lesakay Morgoridge, Chantel Rolle, Altrice Taylor, Beverly Langley | 44.66 |
| 1994 | Central State (OH) | Bridgette Edwards, Beverly Grant, Audrea Sterling, Catherine Pomales | 44.32 |
| 1993 | Central State (OH) | Bridgette Edwards, Carolin Sterling, Audrea Sterling, Deon Hemmings | 45.46 |
| 1992 | Central State (OH) | Alwren Wallace, Carolin Sterling, Layphane Carnagie, Audrea Sterling | 45.52 |
| 1991 | Central State (OH) | Antonette Jones, Carolin Sterling, Alwren Wallace, Audrea Sterling | 44.81 |
| 1990 | Missouri Baptist | Sandra Kidd, Dawn Mills, Kerry Evans, Felicia Amajali | 46.12 |
| 1989 | Prairie View A&M (TX) | Terri Clayton, Wanda Clay, Patti Harris, Shana Ford | 46.03 |
| 1988 | Prairie View A&M (TX) | Kimolyn Vanzant, JoAnne Caraway, Patti Harris, Wanda Clay | 45.76 |
| 1987 | Prairie View A&M (TX) | Wanda Clay, Evan Williams, Patti Harris, Jocelyn Tatum | 48.55 |
| 1986 | Wayland Baptist (TX) | Nzael Kyomo, Comfort Igeh, Starlette Daniels, Althea Thomas | 45.37 |
| 1985 | Prairie View A&M (TX) | Deirdre Jackson, Evan Williams, LaVonda Luckett, Jocelyn Tatum | 45.80 |
| 1984 | Prairie View A&M (TX) | Deirdre Jackson, Evan Williams, Jocelyn Tatum, Norrie McAfee | 45.36 |
| 1983 | Prairie View A&M (TX) | Lynn Gamble, Norrie McAfee, Sheila Labome, Easter Gabriel | 45.06 |
| 1982 | Prairie View A&M (TX) | Sheila Labome, Casandra Graham, Loretta Edwards, Easter Gabriel | 45.25 |
| 1981 | Texas Southern | Donna Lazard, Cora Sherman, Denise Cox, Linda Weekly | 45.41 |
