Totally unsympathetic character, bad science medicine, paper doll secondaries...so why do we watch? Because he's a miserable, mean hearted artiste, with no impulse control, who says and does the things that we sometimes secretly long to say and do.--Mick, on House

"I think it's important that House remains uncompromised. There is a defiance about him that's a kind of strength, and even though it might be belligerent at times, I find it inspiring. He will not suddenly give into the sentimental, even at the end of the show. I find that uplifting, in a twisted and dark way."--Hugh Laurie

For better or for worse, they are bound together. They share a way of looking at the world, and I think they need each other. -Hugh Laurie

Barbara Barnett: There is no question that Wilson and House’s relationship is the most significant in either of their lives.
"All heroic deeds require a cost otherwise they’re not really heroic. There has to be a dragon, there has to be risk, there has to be pain…and he endures that pain, and fights that dragon. And he pays that price in lots of different ways. And he pays it for the sake of seeking out this bigger truth."
―Hugh Laurie about House

Stephen Fry: I became temporarily and completely addicted to 'House, M.D.' and watched the first six seasons in the space of three weeks. At first it was difficult, I'll admit, getting past Hugh Laurie With An American Accent. I kept thinking, 'What the hell's Prince George doing with that syringe and why on earth is he pronouncing lilacs 'li-larks.' Soon, however, I was well and truly sucked in and he BECAME House. I believed in him entirely. I wanted him to be my Doctor. I was wildly disappointed when I visited the surgery for my medication review and the GP was nice to me. Eventually, I watched an episode of 'Blackadder III' and thought, 'What the hell's House doing wearing that stupid wig?'

Wilson: "You know, in some cultures, it's considered almost rude for one friend to spy on another. Of course, in Swedish, the word "friend" can also be translated as "limping twerp"."