What volume of epinephrine (1 mg/ml) needs to be added
to make 50 ml of bupivacaine 0.5% with
epinephrine 1:100,000 ?
Answer:
Method #1
Step #1 1 mg/ml of
epinephrine is 1000 mcg/ml
Step #2: Need 1:100,000 which
is the same as 10 mcg/ml
Step #3: 10 mcgml X 50 ml
= 500 mcg
Step #3: 500 mcg divided
by 1000 mcg/ml of epinephrine is
0.5 ml !
Method #2
X ml epinephine = 50 ml final product 10 mcg epi
1 ml
X ---------- X ---------
= 0.5 ml !
1 ml 1000 mcg epi
