401) "Twenty years from now you will be more disappointed by the things that you didn't do than by the ones you did do. So throw off the bowlines. Sail away from the safe harbor. Catch the trade winds in your sails. Explore. Dream. Discover." --Samuel Clemens (Mark Twain)

402) "It is not because things are difficult that we do not dare; it is because we do not dare that things are difficult." --Lucius Annaeus Seneca

403) "The heart has reasons that reason does not know." --Blaise Pascal

404) "We at times too young for what is old, and too old for what has never been." --Rike

405) "Clothes make me feel fat, but shoes always fit." --Toni Colette (In Her Shoes)

406) "A male gynecologist is like an auto mechanic who never owned a car." --Carrie Snow

407) "In politics, if you want anything said, ask a man; if you want anything done, ask a woman." --Margaret Thatcher

408) "There's so many different ways to be connected to people. There are the people you feel this unspoken connection to, even though there's not even a word for it. There's the people who you've known forever, who know you in this way that other people can't, because they've seen you change...they've let you change." --Angela on My So-Called Life

409) "A FRIEND is one/ To whome one may pour/ Out all the contents/ Of one's heart,/ Chaff and grain together,/ Knowing that the/ Gentlest of hands/ Will take and sift it,/ Keep what is worth keeping/ And with the breath of kindness/ Blow the rest away." --Arabian Proverb

410) "Life is an onion. You peel it off one layer at a time, and sometimes you cry." --Carl Sandburg

411) "My mom said she learned how to swim when someone took her out in the lake and threw her off the boat. I said, 'Mom, they weren't trying to teach you how to swim.'" --Paula Poundstone

412) "A study in the Washington Post says that women have better verbal skills than men. I just want to say to the authors of that study: Duh." --Conan O'Brien

413) "I think that's how Chicago got started. A bunch of people in New York said, "Gee, I'm enjoying the crime and the poverty, but it just isn't cold enough. Let's go west."" --Richard Jeni

414) "Oh, you hate your job? Why didn't you say so? There's a support group for that. It's called EVERYBODY and they meet at the bar." --Drew Carey

415) "Though we travel the world over to find the beautiful, we must carry it with us, or we find it not." --Ralph Waldo Emerson

416) "Be very careful if you make a woman cry, because God counts her tears. The woman came out of a man's rib. Not from his feet to be walked on. Not from his head to be superior, but from the side to be equal. Under the arm to be protected, and next to the heart to be loved."

417) "To have a child is to be given the world to hold in your hands and the entire universe to try and fit inside your heart." --Douglas Pagels>

418) "If you were happy every day of your life, you wouldn't be a human being, you'd be a game show host." --Veronica (Heathers)

419) "Dream your dreams with open eyes and make them come true." --T.E. Lawrence

420) "You make me want to be a better man." --Melvin (As Good as it Gets)

421) "Get busy livin', or get busy dyin'." --Andy (Shawshank Redemption)

422) "Someday somebody's going to ask you a question that you should say yes to." --Old 97's

423) "You do something to me that I can't explain. Would I be out of line if I said - I miss you. --Incubus (I Miss You)

424) "Not all who wander are lost." --J. R. R. Tolkein

425) "If you feel you're under control, you're just not going fast enough." --Mario Andretti

426) "In your eyes I am complete." --Peter Gabriel

427) "When life hands you a lemon, say 'Oh, yeah, I like lemons. What else you got?'." --Henry Rollins

428) "Before you criticize someone, you should walk a mile in their shoes. That way, when you criticize them, you are a mile away from them and you have their shoes." --Frieda Norris

429) "...then I did the simplest thing in the world. I leaned down...and kissed him. And the world cracked open." --Agnes de Mille

430) "I gave her my heart and she gave me a pen." --Lloyd Dobbler (Say Anything)

431) "The world is full of guys. Be a man. Don't be a guy." --Say Anything

432) "That's not a black dress, that's an entire Audrey Hepburn movie." --Jerry Maguire

433) "A kiss is a lovely trick designed by nature to stop speech when words become superfluous." --Ingrid Bergman

434) "The very least you can do in your life is figure out what you hope for. And the most you can do is live right inside that hope. Not admire it from a distance, but live right in it, under its roof." --Barbara Kingsolver

435) "Truly great friends are hard to find, difficult to leave, and impossible to forget."

436) "What will you risk for what you believe?-- and what is your belief worth if you will not risk anything in its defense?" --Michael Kube-McDowell

437) "Going after anything worthwile in life entailed risk, of course. A man of ambition and courage didn't let that stop or delay him. A man accepted the dangers, the element of chance. If he didn't, he won nothing." --John Jakes

438) "You're everything I never knew I always wanted." --Alex to Isabel in 'Fools Rush In'

439) "In most cases, strengths and weaknesses are two sides of the same coin. A strength in one situation is a weakness in another, yet often the person can't switch gears. It's a very subtle thing to talk about strengths and weaknesses because almost always they're the same thing." --Steve Jobs

440) "It's just as difficult to reach a destination you don't have, as it is to come back from a place you have never been." --Zig Ziglar

441) "The wise teacher...knows that fifty-five minutes of work plus five minutes' laughter are worth twice as much as sixty minutes of unvaried work." --Gilbert Highet

442) "The spice of life is battle; the friendliest relations are still a kind of contest; and if we would not forego all that is valuable in our lot, we must continually face some other person, eye to eye, and wrestle a fall whether in love or enmity." --Robert Louis Stevenson

443) "Of all the things you wear, your expression is the most important." --Janet Lane

444) "It was the perfect moment for him to kiss me - for him to anything me." --Angela Chase (MSCL)

445) "What's amazing is when you can feel your life going somewhere, like your life just figured out how to get good, like that second." --Angela Chase

446) "Once upon a time there lived a girl. She lived in a lovely cottage of gingerbread and candy. She was always asleep. One morning she woke up, she woke up." --Angela Chase (poem she writes for school)

447) "I am nothing special; just a common man with common thoughts, and I've led a common life. There are no monuments dedicated to me and my name will soon be forgotten. But in one respect I have succeeded as gloriously as anyone who's ever lived: I've loved another with all my heart and soul; and to me, this has always been enough." --The Notebook (Noah)

448) "I like to feel his eyes on me when I look away." --Before Sunrise (Celine)

449) "If there's any kind of magic in this world, it must be in the attempt of understanding someone, sharing something. I know, it's almost impossible to succeed, but who cares, really? The answer must be in the attempt." --Before Sunrise (Celine)

450) "You can never replace anyone because everyone is made up of such beautiful specific details. --Before Sunset (Celine)

451) "The reality of the other person is not in what he reveals to you, but in what he cannot reveal to you. Therefore, if you would understand him, listen not to what he says but rather what he does not say." --Kahlil Gibran

452) "To know someone here or there with whom you can feel there is understanding in spite of distances or thoughts expressed. That can make life a garden." --Goethe

453) "He who does not understand your silence will probably not understand your words." -- Elbert Hubbard

454) "People think a soul mate is your perfect fit, and that's what everyone wants. But a true soul mate is a mirror, the person who shows you everything that's holding you back, the person who brings you to your own attention so you can change your life. A true soul mate is probably the most important person you'll ever meet, because they tear down your walls and smack you awake." --Elizabeth Berg, "Eat, Pray, Love" If you press me to say why I loved him, I can say no more than it was because he was he, and I was I. --Montaigne

455) "If you cannot inspire a woman with love of you, fill her above the brim with love of herself; all that runs over will be yours." --Charles Caleb Colton

456) "A woman without a man is like a fish without a bicycle." --Gloria Steinem

457) "At the end of the day, there are some things you just can't help but talk about. Some things we just don't want to hear, and some things we say because we can't be silent any longer. Some things are more than what you say, they're what you do. Some things you say because there's no other choice. Some things you keep to yourself. And not too often, but every now and then, some things simply speak for themselves." --Meredith Grey, Grey's Anatomy

458) "[one on one meeting with the Chief] Aren't you gonna say anything or [pause] I'm not gonna break [pause] I'm starting to get a little freaked out, but I'm not gonna break. It’s not because I don't care, because I do care what you think about me, I do. Care. I just can't tell you want you want to hear. Which seems to be a theme in my life right now. Just because you can't say something doesn't mean you don't want to, you can want to very much. You can be with a person and be happy with them and not love them. And you can love somebody and not want to be with them. You don't need to love someone to want them. Now that's frustrating, when what your brain tells you you want and what you actually want don't match up. It’s exhausting. And, well, it’s complicated. But that's life. And life... sucks." --George O'Malley, Grey's Anatomy

459) "No, see, sir, this is the point. Because I can't tell you, I can't tell you what happened in that room. And before I could have; no guilt, no loyalties, no problem. Before--before I wouldn't have even been in that room. I wouldn't have gotten involved. I would have never frozen in surgery, and I would have told him what I thought he should do. I had an edge, sir. I had an edge, and I've lost it, and I need it. I need it back. So, if you could just tell me, how you keep yours and how not to be affected, I know I could be a great surgeon. So if you could just give me the answers, I would really appreciate it." --Cristina Yang, Grey's Anatomy

460) "Stop fighting me. If I say it back right now, you know I'm just saying it because you said it to me. When I, when I say I love you, I want to mean it, because… You just have to give me some time to mean it." --George O'Malley, Grey's Anatomy

461) "Time waits for no man. Time heals all wounds. All any of us can want is more time. Time to stand up. Time to grow up. Time to let go. Time." --Meredith Grey, Grey's Anatomy

462) "At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing where we all keep our distance and pretend not to care about each other, it's usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them. The people that are still with you at the end of the day, those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need." --Meredith Grey, Grey's Anatomy

463) "I understand feeling as small and as insignificant as humanly possible. And how it can actually ache in places you didn't know you had inside you. And it doesn't matter how many new haircuts you get, or gyms you join, or how many glasses of Chardonnay you drink with your girlfriends... you still go to bed every night going over every detail and wonder what you did wrong or how you could have misunderstood. and how in the hell for that brief moment you could think that you were that happy. And sometimes you can even convince yourself that he'll see the light and show up at your door. And after all that, however long all that may be, you'll go somewhere new. And you'll meet people who make you feel worthwhile again. And little pieces of your soul will finally come back. And all that fuzzy stuff, those years of your life that you wasted, that will eventually begin to fade." --The Holiday ~ Iris

464) "For a kiss to be really good, you want it to mean something. You want it to be with someone you can't get out of your head, so that when your lips finally touch you feel it everywhere. A kiss so hot and so deep you never want to come up for air. You can't cheat your first kiss. Trust me, you don't want to. Cause when you find that right person for a first kiss, it's everything." --Alex Karev, Grey's Anatomy

465) "Pain, you just have to ride it out, hope it goes away on its own, hope the wound that caused it heals. There are no solutions, no easy answers, you just breath deep and wait for it to subside. Most of the time pain can be managed but sometimes the pain gets you where you least expect it. Hits way below the belt and doesn't let up. Pain, you just have to fight through, because the truth is you can't outrun it and life always makes more." --Meredith Grey, Grey's Anatomy

466) "I wish there were a rulebook for intimacy. Some kind of guide to tell you when you've crossed the line. It would be nice if you could see it coming, and I don't know how you fit it on a map. You take it where you can get it, and keep it as long as you can. And as for rules, maybe there are none. Maybe the rules of intimacy are something you have to define for yourself." --Meredith Grey, Grey's Anatomy

467) "At the end of the day faith is a funny thing. It turns up when you don't really expect it. It's like one day you realize that the fairy tale may be slightly different than you dreamed. The castle, well, it may not be a castle. And it's not so important happy ever after, just that its happy right now. See once in a while, once in a blue moon, people will surprise you , and once in a while people may even take your breath away." --Meredith Grey, Grey's Anatomy

468) "Communication. It's the first thing we really learn in life. Funny thing is, once we grow up, learn our words and really start talking, the harder it becomes to know what to say. Or how to ask for what we really want." --Meredith Grey, Grey's Anatomy

469) "In the movies, we have leading ladies and we have the best friend. You, I can tell, are a leading lady, but for some reason, you're behaving like the best friend. --The Holiday ~ Arthur Abbott

470) "You're supposed to be the leading lady in your own life, for God's sake!" --The Holiday ~ Iris

471) "I have found almost everything ever written about love to be true. Shakespeare said, "Journeys end in lovers meeting." What an extraordinary thought." --The Holiday ~ Iris

472) "I'm looking for love. Real love. Ridiculous, inconvenient, consuming, can't-live-without-each-other love. And I don't think love is here in this expensive suite in the lovely hotel in Paris." --Carrie, Sex and the City

473) "You're the loves of her life and a guy's just lucky to come in fourth." --Big, Sex and the City

474) "It would be childish of us to deny that our lives weren't changing. But for this night, none of us were going anywhere. That's the thing about really good friends and a really great Manhattan." --Carrie, Sex and the City

475) "Think about it. If you are single, after graduation, there isn't one occasion where people celebrate you... Hallmark doesn't make a "congrats, you didn't marry the wrong guy" card. And where's the flatware for going on vacation alone?" --Carrie, Sex and the City

476) "Maybe our mistakes are what make our fate. Without them, what would shape our lives? Perhaps if we never veered off course, we wouldn't fall in love, or have babies, or be who we are. After all, seasons change. So do cities. People come into your life and people go. But it's comforting to know the ones you love are always in your heart. And if you're very lucky, a plane ride away." --Carrie, Sex and the City

477) "Map out your future – but do it in pencil. The road ahead is as long as you make it. Make it worth the trip." --Jon Bon Jovi

478) *I would rather trust a woman's instinct than a man's reason." --Stanley Baldwin

479) "Each day comes bearing gifts. Untie the ribbons." --Ruth Ann Schanacker

480) "Love one another and you will be happy. It's as simple and as difficult as that." --Michael Leunig

481) "Every day is an opportunity to make a new happy ending." --Anon

482) "That best portion of a good man's life; His little, nameless, unremembered acts of kindness." --William Wordsworth

483) "Sometimes I would rather have people take away years of my life than take away a moment." --Pearl Bailey

484) "Joy is what happens to us when we allow ourselves to recognize how good things really are." --Marianne Williamson

485) "True friendship comes when the silence between two people becomes comfortable." --Dave Tyson Gentry

486) "A person often meets his destiny on the road he took to avoid it." --Jean de La Fontaine

487) "Mankind must remember that peace is not God's gift to his creatures; peace is our gift to each other." --Elie Wiesel

488) "A mother understands what a child does not say." --Jewish Proverb

499) "It is a mistake to look too far ahead. The chain of destiny can only be grasped one link at a time." --Winston Churchill

490) "Home is not where you live, but where they understand you." --Christian Morgenstern

491) "I think, at a child's birth, if a mother could ask a fairy godmother to endow it with the most useful gift, that gift would be curiosity." --Eleanor Roosevelt

492) "For it is in the giving that we receive." --St. Francis of Assisi

493) "Courage is being afraid but going on anyhow." --Dan Rather

494) "In spite of the 6000 manuals on child raising in the bookstores, child raising is still a dark continent and no one really knows anything. You just need a lot of love and luck - and of course, courage." --Bill Cosby

495) "I know well that happiness is in the little things." --John Ruskin

496) "...Yet even in defeat, the courageous Trager secretly clung to the belief that life is not merely a series of meaningless accidents or coincidences. Uh-uh. But rather it's a tapestry of events that culminate in an exquisite, sublime plan... Ultimately Jonathan concluded that if we are to life live in harmony with the universe, we must all possess a powerful faith in what the ancients used to call "fatum", what we currently refer to as destiny. --Serendipity (Dean)

497) "When your heart speaks, take good notes. --Judith Campbell