Is Zithromax helpful?

Zithromax: uses

Zithromax is an antibiotic ( macrolide-type ) used to treat a wide variety of bacterial infections. It works by stopping growth of bacteria.

This antibiotic treats only bacterial infections. It won't work for viral infections ( e. g. , common cold, flu ) . Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

Zithromax: how to use

Take Zithromax by mouth with or without food, usually once a day, or as directed by your doctor. We may take Zithromax with food if stomach upset occurs.

Antibiotics work best when amount of medicine in your body is kept at a constant level. Therefore, take Zithromax at same time each day.

Continue to take Zithromax until full prescribed amount is finished even if symptoms disappear after a few days. Stopping medication too early may allow bacteria to continue to grow, which may result in a relapse of infection.

Antacids may decrease absorption of Zithromax. If you take an antacid, wait at least 2 hours after taking this medication.

Inform your doctor if your condition persists or worsens.

Zithromax: side effects

Stomach upset, diarrhea/loose stools, nausea, vomiting, or stomach/abdominal pain may occur while use Zithromax. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed Zithromax because he or she has judged that benefit to we is greater than risk of side effects. Many people using Zithromax do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

Tell your doctor immediately if any of these highly unlikely but very serious side effects occur:

Seek immediate medical attention if any of these rare but very serious side effects occur:

Zithromax may rarely cause a severe intestinal condition ( pseudomembranous colitis ) due to a resistant bacteria. This condition may occur while use Zithromax weeks after treatment has stopped. Don't use anti-diarrhea products or narcotic pain medications if we have following symptoms because these products may make them worse. Tell your doctor immediately if we develop: persistent diarrhea, abdominal or stomach pain/cramping, or blood/mucus in your stool.

Use of Zithromax for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection ( oral or vaginal fungal infection ) . Contact your doctor if we notice white patches in your mouth, a change in vaginal discharge or other new symptoms.

A serious allergic reaction to Zithromax is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include:

An allergic reaction to Zithromax may return even if we stop drug. If we have an allergic reaction, continue to watch for any of above symptoms for several days after your last dose.

This isn't a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Zithromax: precautions

Before taking Zithromax, tell your doctor or pharmacist if we are allergic to it; or to other macrolide antibiotics such as erythromycin, clarithromycin; or if we have any other allergies.

Before using Zithromax, tell your doctor or pharmacist your medical history, especially of:

Zithromax should be used only when clearly needed during pregnancy. Discuss risks and benefits with your doctor.

Zithromax passes into breast milk. Consult your doctor before breast-feeding.

Zithromax: interactions

See also How to Use section.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring we for them. Do not start, stop, or change dosage of any medicine before checking with them first.

Before using Zithromax, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

Zithromax may decrease effectiveness of combination-type birth control pills. This can result in pregnancy. We may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details.

Other drugs besides Zithromax which may affect the heart rhythm ( QTc prolongation in EKG ) include amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, propafenone, and sparfloxacin among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for more details, and for instructions on how we may reduce your risk of this effect.

This document doesn't contain all possible interactions. Therefore, before using Zithromax, tell your doctor or pharmacist of all products you use. Keep a list of all your medications with you, and share list with your doctor and pharmacist.

Zithromax: overdose

If overdose of Zithromax is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: severe or persistent diarrhea.

Zithromax: notes

Don't share Zithromax with others.

Zithromax has been prescribed for your current condition only. Don't use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases.

Zithromax: missed dose

If you miss a dose Zithromax, use it as soon as we remember. If it's near the time of next dose, skip missed dose and resume your usual dosing schedule. Don't double the dose of Zithromax to catch up.

Zithromax: storage

Store Zithromax at room temperature between 59-86 degrees F ( 15-30 degrees C ) away from light and moisture. Do not store Zithromax in the bathroom. Keep all medicines away from children and pets.

Properly discard Zithromax when it's expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Quality cheap Zithromax

The Correlation Between The Length Of Positive Surgical Margins And Biochemical Recurrence After Radical Prostatectomy For Prostate Cancer

UroToday. com - The presence of positive surgical margins in a radical prostatectomy ( RP ) specimen is an important negative prognostic factor, although the length of the positive margins was not an independent predictive factor for biochemical recurrence ( BCR ) in most studies. The aim of this study is to correlate length and Gleason grade of positive resection margin with BCR after RP.

The Dutch researchers analyzed the data of 218 consecutive RP specimens with positive surgical margins. All RP specimens were sectioned at 4-mm intervals and completely embedded. Evaluation was done by one uropathologist with regard to the length of positive margins ( mm ) and the highest Gleason grade in positive margins. BCR was defined as two consecutive PSA levels above 0. 10ng/ml. Data were analyzed in proportional hazards models.

In 25 patients post-operative PSA didn't drop to zero and another 56 patients received adjuvant hormonal treatment or radiotherapy, leaving a group of 137 patients to be analyzed for BCR. The median follow-up was 38. 9 months. In group of 218 patients, length of positive margins ranged from 0. 4 to 174. 5 mm ( median 10. 0mm; mean 19. 1 ) and was associated with pre-operative PSA 0. 001 ) , pathologic stage ( p = 0. 001 ) , tumor volume ( p = 0. 032 ) , number of positive sites ( p <0. 0001 ) and Gleason grade at positive margin ( p = 0. 001 ) , but not with Gleason score ( p = 0. 06 ) . The distribution of locations of positive margins was dorsal ( 43, 6% ) , anterior ( 33, 5% ) , apical ( 32, 1% ) , posterolateral ( 18, 8% ) , basal ( 18, 3% ) and at seminal vesicles ( 3, 7% ) . The mean length of positive margins of 25 patients with persistent increased post-operative PSA levels was significantly higher ( 32. 4mm; p=0. 005 ) . In group of 137 patients, the 5-year biochemical recurrence free survival ( RFS ) rate was 74%. The RFS for patients with positive margins <10mm and > 10mm was 80% and 65% respectively. In multivariate analyses BCR was associated with increasing length, but not with preoperative PSA, pathological stage, Gleason score, tumor volume or Gleason grade at resection margin.

The presenters conclude that length of positive margins is an independent predictive factor for PSA recurrence.

Presented by H Max Bruins, MD, Inge M van Oort, MD, Lambertus A Kiemeney, MD, Christina A Hulsbergen-van de Kaa, MD, J Alfred Witjes, MD, at Annual Meeting of American Urological Association ( AUA ) - May 17 - 22, 2008. Orange County Convention Center - Orlando, Florida, USA

Reported by UroToday. com Contributing Editor Christopher P. Evans, MD, FACS

UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice.

To access latest urology news releases from UroToday , go to: www. urotoday. com

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