In zootomy and dermatology, skin is an organ of the integumentary system composed of a layer of tissues that protect underlying muscles and organs. As the interface with the surroundings, it plays the most important role in protecting against pathogens. Its other main functions are insulation and temperature regulation, sensation and vitamin D and B synthesis. Skin has pigmentation, provided by melanocytes, which absorbs some of the potentially dangerous radiation in sunlight. It also contains DNA repair enzymes which reverse UV damage, and people who lack the genes for these enzymes suffer high rates of skin cancer. One form predominantly produced by UV light, malignant melanoma, is particularly invasive, causing it to spread quickly, and can often be deadly. Human skin pigmentation varies among populations in a striking manner. This has sometimes led to the classification of people on the basis of skin color. See the article on human skin color. The skin is often known as "the largest organ in the human body". This applies to exterior surface, as it covers the body, appearing to have the largest surface area of all the organs. Moreover, it applies to weight, as it weighs more than any single internal organ, accounting for about 15 percent of body weight. For the average adult human, the skin has a surface area of between 1.5-2.0 square metres, most of it is between 2-3 mm thick. The average square inch of skin holds 650 sweat glands, 20 blood vessels, 1000 melanocytes, and more than a thousand nerve endings. Skin is composed of the epidermis and the dermis. Below these layers lies the hypodermis(subcutaneous adipose layer), which is not usually classified as a layer of skin. The dermis lies below the epidermis and contains a number of structures including blood vessels, nerves, hair follicles, smooth muscle, glands and lymphatic tissue. It consists of loose connective tissue otherwise called areolar connective tissue - collagen, elastin and reticular fibres are present. Erector muscles, attached between the hair papilla and epidermis, can contract, resulting in the hair fibre pulled upright and consequentially goose bumps. The dermis can be split into the papillary and reticular layers. The papillary layer is outermost and extends into the dermis to supply it with vessels. It is composed of loosely arranged fibres. Papillary ridges make up the lines of the hands. The reticular layer is more dense and is continuous with the hypodermis. It contains the bulk of the structures (such as sweat glands). The reticular layer is composed of irregularly arranged fibres and resists stretching. Skin can be dividided into thick and thin types. Thick skin is present on the soles of the feet and the palms of the hands. It has a larger stratum corneum with a higher keratin content. Thick skin does not grow hair; its purpose is to help grip. Thin skin is present on the bulk of the body and has a smaller stratum corneum and fewer papillae ridges. It has hair and is softer and more elastic. The characteristics of the skin, including sensory nerve density and the type of hair, vary with location on the body. Functions of the skin are disturbed when it is dirty and it becomes more easily damaged. The release of antibacterial compounds decreases. Dirty skin is more prone to develop infections. Cosmetics should be used carefully because these may cause allergic reactions. Each season requires suitable clothing in order to facilitate the evaporation of the sweat. Sunlight, water and air play an important role in keeping the skin healthy.
Definitions and terms on this pageAcne
- An inflammatory disease of the sebaceous glands and hair follicles of the skin that is marked by the eruption of pimples or pustules, especially on the face.
Bacteria
- Microscopic unicellular prokaryotic organisms characterized by the lack of a membrane-bound nucleus and membrane-bound organelles.
Dermis
- The sensitive connective tissue layer of the skin located below the epidermis, containing nerve endings, sweat and sebaceous glands, and blood and lymph vessels.
Epidermis
- The outer, protective, nonvascular layer of the skin of vertebrates, covering the dermis.
Hypodermis
- A subcutaneous layer of loose connective tissue containing a varying number of fat cells.
Pimples
- A small swelling of the skin, usually caused by acne; a papule or pustule.
Ultraviolet radiation
- Invisible electromagnetic radiation between visible violet light and X rays.
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