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"Human factors" is a term used mainly in the United States. Variants include "human factors engineering", an extension of an earlier phrase, "human engineering". In Europe and the rest of the world, the term "ergonomics" is more prevalent. Cognitive ergonomics is another term used. Document Holders and Ergonomic Office Supplies.

"Human factors" is an umbrella term for several areas of research that include human performance, technology, design, and human-computer interaction. It is a profession that focuses on how people interact with products, tools, procedures, and any processes likely to be encountered in the modern world.

Human factors practitioners can come from a variety of backgrounds; though predominantly they are Psychologists (Cognitive, Perceptual, and Experimental) and Engineers. Designers (Industrial, Interaction, and Graphic), Anthropologists, Technical communication Scholars and Computer Scientists also contribute.

Whereas ergonomics tends to focus on the anthropometrics for optimal human-machine interaction, human factors is more focused on the cognitive and perceptual factors.