U.S. Federal Route 31 is a main north-south highway in Bartholomew County. It runs through the center of the county. U.S. Rt. 31 passes through the following town in Bartholomew County. Columbus U.S. Rt. 31 is multi-plexed in Bartholomew County. Indiana State Route 46, near Columbus. U.S. Rt. 31 intersects the following highways in Bartholomew County. Interstate 65, near Taylorsville. Indiana State Route 46, near Columbus. Indiana State Route 7, near Columbus. Indiana State Route 46, near Columbus.
