Business U.S. Federal Route 51 runs along a narrow two-lane road thtough the county seat of De Witt County. This is the original path of U.S. Rt. 51, til it was by-passed along the westside of Clinton. BUSN. U.S. Rt. 51 passes through the following town in De Witt County. Clinton
BUSN. U.S. Rt. 51 is not multi-plexed in De Witt County. BUSN U.S. Rt. 51 intersects the following highways in De Witt County. U.S. Rt. 51, on the northside of Clinton.