Illinois State Route 100 runs breifly in the southwestern tip of Greene County. IL St Rt 100 passes through the following town in Greene County. East Hardin
IL St Rt 100 is multi-plexed in Greene County. Illinois State Route 16, through Greene County.
IL St Rt 100 intersects the following highway in Greene County. Illinois State Route 16, at East Hardin.
WB IL St Rt 16/NB IL St Rt 100 near East Hardin. NB IL St Rt 100 in East Hardin near the Illinois River.
