Illinois State Route 104 runs east-west in Northern Pike County. This passes through mostly rural areas of the county. It is a two-lane alternate to Interstate 72/U.S. Rt. 36 for traffic going between Jacksonville and Quincy. IL St Rt 104 passes through the following towns in Pike County. Fishhook Chambersburg
IL St Rt 104 is not multi-plexed in Pike County. IL St Rt 104 intersects the following highways in Pike County. Illinois State Route 107, near Perry.
A junction marker on NB IL St Rt 107. EB IL St Rt 104 east of IL St Rt 107. A Pike County mile marker. EB IL St Rt 104 west of Chambersburg. EB IL St Rt 104 in Chambersburg. EB IL St Rt 104 east of Chambersburg. EB IL St Rt 104 near IL St Rt 99. EB IL St Rt 104 near the Illinois River.
