Business U.S. Federal Route 75 runs north-south in Sioux City. This runs along a old alignment of U.S. Rt. 75. BUSN U.S. Rt. 75 passes through the following town in Woodbury County. Sioux City BUSN U.S. Rt. 75 is multi-plexed in Woodbury County. Interstate 29, at Sioux City. BUSN U.S. Rt. 75 corsses the following highways in Woodbury County. Interstate 29, at Sioux City. Interstate 129, at Sioux City. U.S. Rt. 20, at Sioux City. U.S. Rt. 75, at Sioux City. Interstate 29, at Sioux City. U.S. Rt. 20, at Sioux City. (NO INTERCHANGE) U.S. Rt. 75, at Sioux City. (NO INTERCHANGE) BUSN U.S. Rt. 20, at Sioux City. U.S. Rt. 75, at Sioux City.
