U.S. Federal Route 218 is a north-south highway in the southwest corner of Chickasaw County. U.S. Rt. 218 does not pass through any towns in Chickasaw County. U.S. Rt. 218 is multi-plexed in Chickasaw County. Iowa State Route 27, through Chickasaw County.
U.S. Rt. 218 intersects the following highway in Chickasaw County. Iowa State Route 346, near Nashua.