U.S. Federal Route 61 is the main north-south highway in Des Moines County. From the Louisa/Des Moines County Line to Burlington, this highway in mostly two lanes wide. South of Burlington this is a four-lane divided highway. U.S. Rt. 61 passes through the following towns in Des Moines County. Mediapolis Burlington U.S. Rt. 61 is not multi-plexed in Des Moines County. U.S. Rt. 61 intersects the following highways in Des Moines County. U.S. Rt. 34, at Burlington.
A BGS on WB U.S. Rt. 34. SB U.S. Rt. 61 south of Burlington. SB U.S. Rt. 61 near the Des Moines/Lee County Line.
