U.S. Federal Route 61 is a north-south highway in West-Central Jackson County. Near Maquoketa it runs along a expressway. From Iowa State Route 64 to the Jackson/Dubuque County Line it is a multi-lane highway. U.S. Rt 61 passes through the following towns in Jackson County. Maquoketa
Hurstville U.S. Rt. 61 is not multi-plexed in Jackson County. U.S. Rt. 61 intersects the following highways in Jackson County. Iowa State Route 64, at Maquoketa.