Illinois State Route 49 runs very breifly through the southeastern portion of Cumberland County. This mostly runs near the town of Hazel Dell. IL St Rt 49 does not pass through any towns in Cumberland County. IL St Rt 49 is not multi-plexed in Cumberland County. IL St Rt 49 does not intersects any highways in Cumberland County.
SB IL St Rt 49 at the Cumberland/Clark County Line. SB IL St Rt 49 north of the Cumberland/Jasper County Line.
