U.S. Federal Route 150 runs north-south through Henry County. It runs along the western county line. U.S. Rt. 150 passes through the following towns in Henry County. Alpha
Orion
Sunny Hill U.S. Rt. 150 is multi-plexed in Henry County. Illinois State Route 17, near Alpha.
U.S. Rt. 150 intersects the following highways in Henry County. Illinois State Route 17, near Alpha.
WB U.S. Rt. 150 at IL St Rt 17. A Henry County mile marker. A junction marker on WB U.S. Rt. 150/IL St Rt 17. A junction marker on EB IL St Rt 17. WB U.S. Rt. 150 south of Orion.