U.S. Federal Route 50 runs east-west across the center of Richland County. The original alignment of this highway is now numbered Illinois State Route 250. U.S. Rt. 50 was re-routed to the south of Olney. U.S. Rt. 50 does not pass through towns in Richland County. U.S. Rt 50 is multi-plexed in Richland County. Illinois State Route 250, from Olney to the Richland/Lawrence County Line.