U.S. Federal Route 51 is a north-south highway in Marshall County. This runs along the Interstate 39 right-of-way the entire length of the county. U.S. Rt. 51 does not pass through any towns in Marshall County. U.S. Rt. 51 is multi-plexed in Marshall County. Interstate 39, throughout Marshall County.
U.S. Rt. 51 intersects the following highway in Marshall County. Illinois State Route 17, near Wenona.
SB I-39/U.S. Rt. 51 near the La Salle/Marshall County Line.