Indiana State Route 246 runs east-west across Southern Vigo County. IN St Rt 246 passes through the following towns in Vigo County. Prairie Creek Lewis IN St Rt 246 is not multi-plexed in Vigo County. IN St Rt 246 intersects the following highways in Vigo County. Indiana State Route 63, at Prairie Creek. U.S. Rt. 41, near Farmersburg. U.S. Rt. 150, near Farmersburg. Indiana State Route 159, at Lewis.
A junction marker on NB U.S. Rt. 41/WB U.S. Rt. 150.
