U.S. Federal Route 78 runs east-west across Central Marshall County. It enters the county from Benton County, near Potts Camp, and runs to De Soto County, near Byhalia. U.S. Rt. 78 does not pass through any towns in Marshall County. U.S. Rt. 78 is multi-plexed in Marshall County. Future Interstate 22, through Marshall County. U.S. Rt. 78 intersects the following highways in Marshall County. Mississippi State Route 4, near Holly Springs. Mississippi State Route 7, near Holly Springs. Mississippi State Route 309, near Byhalia.
WB U.S. Rt. 78 near Lake Center. WB U.S. Rt. 78 in the Holly Springs Forest. WB U.S. Rt. 78 near Holly Springs. WB U.S. Rt. 78 near Byhalia. WB U.S. Rt. 78 near the Marshall/De Soto County Line.
