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Truong, Amy

Lam, Maria

Period 2, H Bio

April 30, 2003

 

 

DIABETES

 

 

Diabetes is a disease in which the body does not produce or properly use insulin.  Insulin is a hormone that is needed to convert sugar, starches and other food into energy needed for daily life.  The cause of diabetes continues to be a mystery, although both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

There are three major types of diabetes:

Type 1:

Results from the body’s failure to produce insulin, the hormone that “unlocks” the cells of the body, allowing glucose to enter and fuel them.  It is estimated that 5-10% of Americans who are diagnosed with diabetes have type 1 diabetes. 

Type 2:

Results from insulin resistance (a condition in which the body fails to properly use insulin), combined with relative insulin deficiency.  Approximately 90-95% (16 million) have type 2 diabetes. 

Gestational diabetes affects about 4% of all pregnant women - about 135,000 cases in the United States each year. 

Type 2 diabetes is the most common form of diabetes.  In type 2 diabetes, either the body does not produce enough insulin or the cells ignore the insulin.  Insulin is necessary for the body to be able to use sugar.  Sugar is the basic fuel for the cells in the body, and insulin takes the sugar from the blood into the cells.  When glucose builds up in the blood instead of going into cells, it can cause two problems:

·         Cells may be starved for energy.

Over time, high blood glucose levels may hurt your eyes, kidneys, nerves or heart.

 

(OHSU Health.com - Diabetes)

(CDC's Diabetes Program - Publications & Products - National Diabetes Fact Sheet - National Estimates on Diabetes)

 

About 11.1 million people are diagnosed while 5.9 million people are undiagnosed. In 1999, approximately 450,000 deaths occurred among people with diabetes aged 25 years and older. This figure represents about 19% of all deaths in the United States in people aged 25 years and older. The risk for death among people with diabetes is about 2 times that of people without diabetes. However, the increased risk associated with diabetes is greater for younger people (that is, 3.6 times for people aged 25-44 years versus 1.5 for those aged 65-74 years) and women (that is, 2.7 times for women aged 45-64 years versus 2.0 for men in that age group). Diabetes was the sixth leading cause of death listed on U.S. death certificates in 1999. This is based on the 68,399 death certificates in which diabetes was listed as the underlying cause of death. Diabetes was listed as a contributing cause of death on an additional 141,265 death certificates. However, many decedents with diabetes do not have the disease entered on their death certificate; only about 35% to 40% have it listed anywhere on the certificate and only about 10% to 15% have it listed as the underlying cause of death.

This is based on the 68,399 death certificates in which diabetes was listed as the underlying cause of death. Approximately 15.7 million Americans have diabetes. The American Diabetes Assn. estimates that this disease costs the nation $98 billion a year in medical care, lost wages, and disability.

Diabetes is the leading cause of blindness among working-age adults. If people with diabetes receive appropriate screening and care, blindness could be prevented. Diabetes is the cause of kidney failure, affecting about 33,000 individuals each year. More than half of lower-limb amputations occur among people with diabetes; 86,000 diabetes-related amputations are performed annually.

Statistically 8.6 percent of the people ages 20 or older have diabetes out of 16.9 million. 20.1 percent of all people age 65 years or older out of 7 million have diabetes. 8.3 percent of all men out of 7.8 million have diabetes. 8.9 percent of all women out of 9.1 million have diabetes. 7.8 percent of all non-Hispanic whites out of 11.4 million have diabetes.

The treatment for people with type 1 diabetes would be insulin delivered by a pump or injections. People with type 2 diabetes can maintain their blood glucose by a careful diet and exercise program, losing excess weight, and taking oral medication. People with diabetes also need to take medications to control their cholesterol level and their blood pressure. Among adults with diagnosed diabetes, about 11 percent take both insulin and oral medications, 22 percent take insulin only, 49 percent take oral medications only, and 17 percent do not take either insulin or oral medications.

Diabetes symptoms are: Frequent urination, excessive thirst, unexplained weight loss, extreme hunger, sudden vision changes, numbness in hands or feet, tiredness, very dry skin, sores which heal slowly, and more infections than usual. Nausea, vomiting, or stomach pains may accompany some of these symptoms in the abrupt onset of insulin-dependent diabetes, now called type 1 diabetes.

A number of studies have shown that regular physical activity can significantly reduce the risk of developing type 2 diabetes. It also appears to be associated with obesity. Researchers are making progress in identifying the exact genetics and "triggers" that predispose some individuals to develop type 1 diabetes, but prevention, as well as a cure, remains elusive. (American Diabetes Association)

BIBLIOGRAPHY

 

1.      http://www.ohsuhealth.com/diabetes/facts.asp

 

2.      http://www.cdc.gov/diabetes/pubs/estimates.htm

 

3.      http://www.diabetes.org/main/application/commercewf

 

4.      The Diabetic's Book: All Your Questions Answered by June Biermann and Barbara Toohey