Pharmacology and Toxicology Quizzes  

Drug Metabolism Quiz 1

1- Chemical compound foreign to a living organism
xenobiotic
metabolite
drug
toxicant


2- Drug activated by metabolism
ibuprophen
codeine
nerve gases
diazepam


3- Are usually genetically engineered to be used in metabolic testing
microsomes
enzymes
hepatocytes
all of the above


4- Enzyme induction does NOT increase
enzyme activity
bioavailability of oral drugs
hepatic clearance
metabolites


5- Aryl hydrocarbons induce CYP1A by binding to
Ah receptor
PPAR
CAR
PXR


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Answers:

1- Chemical compound foreign to a living organism
Answer: xenobiotic


2- Drug activated by metabolism
Answer: codeine


3- Are usually genetically engineered to be used in metabolic testing
Answer: enzymes


4- Enzyme induction does NOT increase
Answer: bioavailability of oral drugs


5- Aryl hydrocarbons induce CYP1A by binding to
Answer: Ah receptor