Pharmacology and Toxicology Quizzes
1- Chemical compound foreign to a living organism xenobiotic metabolite drug toxicant
2- Drug activated by metabolism ibuprophen codeine nerve gases diazepam
3- Are usually genetically engineered to be used in metabolic testing microsomes enzymes hepatocytes all of the above
4- Enzyme induction does NOT increase enzyme activity bioavailability of oral drugs hepatic clearance metabolites
5- Aryl hydrocarbons induce CYP1A by binding to Ah receptor PPAR CAR PXR
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Answers:
1- Chemical compound foreign to a living organism Answer: xenobiotic
2- Drug activated by metabolism Answer: codeine
3- Are usually genetically engineered to be used in metabolic testing Answer: enzymes
4- Enzyme induction does NOT increase Answer: bioavailability of oral drugs
5- Aryl hydrocarbons induce CYP1A by binding to Answer: Ah receptor