1- Isozymes have
similar catalytic properties
different isoelectric points
the same physical properties
the first two are correct

2- Fate of xenobiotics in the body
deactivation
activation
complex with enzyme
all of the above

3- Not a Phase 2 reaction
conjugation
glucoronization
ester cleavage
oxazepam oxazepam glucuronide

4- False about microsomes
are subcellular fractions of mostly liver ER
contain Phase 1 and Phase 2 enzymes
human liver microsomes are easy to obtain
are stable and convenient to use

5- False about metabolite quantification
is usually indirect
sample is usually treated to degrade conjugates prior to assay
enzymes are used to degrade conjugate metabolites
none of the above

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Answers:

1- Isozymes have
Answer: similar catalytic properties

2- Fate of xenobiotics in the body
Answer: all of the above ( deactivation OR activation OR complex with enzyme)

3- Not a Phase 2 reaction
Answer: ester cleavage

4- Not a common enzyme or receptor inducer
Answer: CYP2E1

5- False about metabolite quantification
Answer: none of the above