Pharmacology and Toxicology Quizzes  

G-proteins Quiz 1

1- Size of the beta subunit
8 to 10 kD
20 to 30 kD
35 to 36 kD
39 to 46 kD


2- Activated by GNEFs
Ras
small G-proteins
alpha subunit
the first two are correct


3- It is activated by Ras and in turn activates MAP kinases
GNEF
MAPKKK
ERKS
JNKS


4- Phosphorilates a kinase when active
small G-protein
Ras
GNEF
the first two are correct


5- Has low intrinsic GTPase activity
alpha subunit
beta/gamma complex
small G-protein
GAP


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Answers:

1- Size of the beta subunit
Answer: 35 to 36 kD


2- Activated by GNEFs
Answer: the first two are correct (Ras AND small G-proteins)


3- It is activated by Ras and in turn activates MAP kinases
Answer: MAPKKK


4- Phosphorilates a kinase when active
Answer: the first two are correct (small G-protein AND Ras)


5- Has low intrinsic GTPase activity
Answer: small G-protein