Pharmacology and Toxicology Quizzes
1- G-proteins do not bind to an intracellular effector molecule get activated by binding GTP have intrinsic GTPase activity convert GDP to GTP
2- Not a G-Protein GNEF heterotrimetric small Ras
3- Approximate size of a small G-protein 8 to 10 kD 20 to 30 kD 35 to 36 kD 39 to 46 kD
4- A G-protein participates in transduction if agonist binding is stimulated by GTP effector activity is altered by agonist and GTP Pertussin toxin augments the effect Cholera toxin blocks the effect
5- May activate transcription factors GNEF MAPKKK Ras ERKS
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Answers:
1- G-proteins do not Answer: convert GDP to GTP
2- Not a G-Protein Answer: GNEF
3- Approximate size of a small G-protein Answer: 20 to 30 kD
4- A G-protein participates in transduction if Answer: effector activity is altered by agonist and GTP
5- May activate transcription factors Answer: ERKS