Pharmacology and Toxicology Quizzes  

G-proteins Quiz 2

1- G-proteins do not
bind to an intracellular effector molecule
get activated by binding GTP
have intrinsic GTPase activity
convert GDP to GTP


2- Not a G-Protein
GNEF
heterotrimetric
small
Ras


3- Approximate size of a small G-protein
8 to 10 kD
20 to 30 kD
35 to 36 kD
39 to 46 kD


4- A G-protein participates in transduction if
agonist binding is stimulated by GTP
effector activity is altered by agonist and GTP
Pertussin toxin augments the effect
Cholera toxin blocks the effect


5- May activate transcription factors
GNEF
MAPKKK
Ras
ERKS


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Answers:

1- G-proteins do not
Answer: convert GDP to GTP


2- Not a G-Protein
Answer: GNEF


3- Approximate size of a small G-protein
Answer: 20 to 30 kD


4- A G-protein participates in transduction if
Answer: effector activity is altered by agonist and GTP


5- May activate transcription factors
Answer: ERKS