1- Gs activation
leads to cAMP formation
inhibits adenylyl cyclase
is due to phosphorylation
none of the above

2- Adenylyl cyclase does not have
a long intracellular N-terminus
two hydrophobic stretches
12 transmembrane helices
two intracellular catalytic domains

3- Not true about PKA
is a dimer
has four subunits
has two catalytic subunits
each regulatory subunit binds one cAMP molecule

4- Not a regulator of the cAMP/PKA cascade
Gs and Gi
phosphodiesterase
CREB
forkolin

5- Does not activate phosphodiesterase
calcium
M1 and M2
phosphorylation
cGMP

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Answers:

1- Gs activation
Answer: inhibits adenylyl cyclase

2- Adenylyl cyclase does not have
Answer: a long intracellular N-terminus (has a short intracellular N-terminus)

3- Not true about PKA
Answer: each regulatory subunit binds one cAMP molecule (each bind 2 molecules)

4- Not a regulator of the cAMP/PKA cascade
Answer: CREB

5- Does not activate phosphodiesterase
Answer: M1 and M2