Pharmacology and Toxicology Quizzes
1- Soluble guanylyl cyclases contain heme groups have alpha-1 and beta-1 subunits are homodimers the first two are correct
2- Membrane bound guanylyl cyclases are activated by atrial natriuretic peptide Ca2+ NO G-proteins
3- PKA phosphorylates tyrosine residues serine or threonine residues phosphodiesterases all of the above
4- cGMP depolarizes rod cells by binding Na+ channels increasing phosphodiesterase activity decreasing NO levels none of the above
5- Not a form of NOS endothelial epithelial neuronal inducible
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Answers:
1- Soluble guanylyl cyclases Answer: the first two are correct (contain heme groups AND have alpha-1 and beta-1 subunits)
2- Membrane bound guanylyl cyclases are activated by Answer: atrial natriuretic peptide
3- PKA phosphorylates Answer: serine or threonine residues
4- cGMP demoralizes rod cells by Answer: binding Na+ channels
5- Not a form of NOS Answer: epithelial