Pharmacology and Toxicology Quizzes  

Lipases and IP3 Quiz 1

1- Lipases
hydrolyze triacylglycerols
form diacylglycerols
liberate fatty acidss
all of the above


2- Can hydrolyze phosphatidylserine
PLA2
PLC
PLD
diacylglycerol lipase


3- Enzyme that cleaves at the blue line

PLA2
PLC
PLD
PLA2 and diacylglycerol lipase


4- Phospholipase C cleaves ___ to release send messengers
IP3
PIP2
DAG
all of the above


5- The high homology region in PLC isozymes contains the
Gq alpha binding site
transmembrane domain
catalytic activity
the las two are correct


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Answers:

1- Lipases
Answer: all of the above (hydrolyze triacylglycerols AND form diacylglycerols AND liberate fatty acids as second messengers)


2- Can hydrolyze phosphatidylserine
Answer: PLC


3- Enzyme that cleaves at the blue line

Answer: PLC


4- Phospholipase C cleaves ___ to release send messengers
Answer: PIP2


5- The high homology region in PLC isozymes contain
Answer: catalytic activity